ID A0A0J8R419_COCIT Unreviewed; 586 AA.
AC A0A0J8R419;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 03-MAY-2023, entry version 28.
DE RecName: Full=GP-PDE domain-containing protein {ECO:0000259|PROSITE:PS51704};
GN ORFNames=CISG_07499 {ECO:0000313|EMBL:KMU79135.1};
OS Coccidioides immitis RMSCC 3703.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=454286 {ECO:0000313|EMBL:KMU79135.1, ECO:0000313|Proteomes:UP000054559};
RN [1] {ECO:0000313|Proteomes:UP000054559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 3703 {ECO:0000313|Proteomes:UP000054559};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; DS268171; KMU79135.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J8R419; -.
DR STRING; 454286.A0A0J8R419; -.
DR Proteomes; UP000054559; Unassembled WGS sequence.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR PANTHER; PTHR22958:SF1; GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1; 1.
DR PANTHER; PTHR22958; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF03009; GDPD; 1.
DR SMART; SM00248; ANK; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS51704; GP_PDE; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000054559}.
FT REPEAT 15..47
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 254..576
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
SQ SEQUENCE 586 AA; 63793 MW; 2DABD4BD8258551E CRC64;
MSHSMASIDV AETTRGWTPL ILACIMGHLE IVEILLQAKA SHTLVDRRGW TAKEHAAFRG
HLHIANLLPM HESLGPFGGP SNLQPGTVSS SFTTKRDESC LVLNLGPMQR NKQMAAVALN
FDSTPHPESF SIEVSLPGGP SYLLQLPILD DASNPLLFPV GKSATPQIIF KLFRGVGTGG
QKGPLVGGGT ALLENACPSC TPDHESLIRT RSISIISKNT LDFIGTVSFT YVIAKPYAST
GRPSAQLIPI SNSVQLVGHR GFGQNTAERD YLQLGENTVE VGQSCLSAKT MGASFVEVTR
DLVPIIYHDF SLSESGTDVP IHDVSLNQFL YSGKSALLDD LVRSLPNDRA CQRNPRSQSL
TRYDDKFASA NYRLQHTVDF MKKGFKPNSQ GTSIQSPFAT LEDLFIKLPK DLGFVIELKY
PRPHEAADAS VAPVAIEVNA FIDVILDKIH RFGAGRNIVL ASFTPEICIL LSRKARGYPI
MFITNAGKRP ITDMEKRGAS LQVAIQFARQ WNFTGVVLAA ETFLLCPRLI QYVQRSGLLC
ASYGLVNNVP ENAKVQVDAG IDMLIVDRVG LIAKALASTQ EVVNRN
//
