ID A0A0J8R4Y2_COCIT Unreviewed; 355 AA.
AC A0A0J8R4Y2;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:KMU79475.1};
GN ORFNames=CISG_01893 {ECO:0000313|EMBL:KMU79475.1};
OS Coccidioides immitis RMSCC 3703.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=454286 {ECO:0000313|EMBL:KMU79475.1, ECO:0000313|Proteomes:UP000054559};
RN [1] {ECO:0000313|Proteomes:UP000054559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 3703 {ECO:0000313|Proteomes:UP000054559};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; DS268123; KMU79475.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J8R4Y2; -.
DR STRING; 454286.A0A0J8R4Y2; -.
DR Proteomes; UP000054559; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd05289; MDR_like_2; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43482; PROTEIN AST1-RELATED; 1.
DR PANTHER; PTHR43482:SF1; PROTEIN AST1-RELATED; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054559}.
FT DOMAIN 35..355
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 355 AA; 39131 MW; 37113F8FFA9303FE CRC64;
MDTMQPTGAS EELIPPTMPA VYLPTHPYVK HRKPGPSNLV YRADFPTPTP TETQYLIKVQ
AAAVCRGELE WPHLLHRRET GAVIAHDICG TVLSTPFTDE HLRDGPKFKV GDRVFGLIEP
SRDGGAADCV AAEEDELAFK PQNISAVEAA SIPLPALMAY QGLFEQLRVN DWLKEVHGVH
KPLRLLILNG ASSVGIHAIQ MLRSKSLLPS ASICIFATTN SKQQSSFLRD KFHVDEVIDC
AENPDLVEAW VQKGWAPVHL VLDCIGGKAH RQAHDEKIIC KNGAITTTVG AESEVREASK
NQHPHSQFVS IEPNGKHLEI IGKLVEKGEL TPYVDKVFEL HEVKEAMTFC RSRGA
//
