ID   A0A0J8R9J9_COCIT        Unreviewed;       779 AA.
AC   A0A0J8R9J9;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=pH-response regulator protein palF/RIM8 {ECO:0000313|EMBL:KMU80483.1};
GN   ORFNames=CISG_02334 {ECO:0000313|EMBL:KMU80483.1};
OS   Coccidioides immitis RMSCC 3703.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=454286 {ECO:0000313|EMBL:KMU80483.1, ECO:0000313|Proteomes:UP000054559};
RN   [1] {ECO:0000313|Proteomes:UP000054559}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RMSCC 3703 {ECO:0000313|Proteomes:UP000054559};
RX   PubMed=20516208; DOI=10.1101/gr.103911.109;
RA   Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA   Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA   Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA   FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA   Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA   Taylor J.W., Rounsley S.D.;
RT   "Population genomic sequencing of Coccidioides fungi reveals recent
RT   hybridization and transposon control.";
RL   Genome Res. 20:938-946(2010).
CC   -!- SIMILARITY: Belongs to the arrestin family. PalF/RIM8 subfamily.
CC       {ECO:0000256|ARBA:ARBA00037950}.
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DR   EMBL; DS268124; KMU80483.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0J8R9J9; -.
DR   STRING; 454286.A0A0J8R9J9; -.
DR   Proteomes; UP000054559; Unassembled WGS sequence.
DR   Gene3D; 2.60.40.640; -; 1.
DR   InterPro; IPR014752; Arrestin-like_C.
DR   InterPro; IPR011021; Arrestin-like_N.
DR   InterPro; IPR011022; Arrestin_C-like.
DR   InterPro; IPR014756; Ig_E-set.
DR   PANTHER; PTHR11188; ARRESTIN DOMAIN CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR11188:SF161; PH-RESPONSE REGULATOR PROTEIN PALF_RIM8; 1.
DR   Pfam; PF02752; Arrestin_C; 1.
DR   Pfam; PF00339; Arrestin_N; 1.
DR   SMART; SM01017; Arrestin_C; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054559}.
FT   DOMAIN          291..461
FT                   /note="Arrestin C-terminal-like"
FT                   /evidence="ECO:0000259|SMART:SM01017"
FT   REGION          202..279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          510..700
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        207..223
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        224..275
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        511..559
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        567..591
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        595..614
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        640..692
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   779 AA;  85258 MW;  D87BA0696796218D CRC64;
     MALDSPNGDA TSASPARKRS ILSKFTNRFG NRNRNISEFY IQPDDPWRSY SPGDIVDGSV
     CLVVVKPVRI THLVVCLHGY AKVYKNPVAP GETAEDSGFP GTGRGRRNGE YLGNGLATLF
     EDEIVLCGDG RLKEGIYKFR FELCFPPYSL PSSINFERGT ISYVITSTLT RPTTISPTIS
     CDKRILLLET IDIANLPPPK PRVISLEPIS KRSKTRSKTK STSSEMPRRA SSLEPQSSDS
     GPPLSPVPSE RSNSSCVSNS TQSFQIVSEP SSARCGAQRN DDLWSGATSS ASQEITATTK
     VLRAGVLPGD LLPVNISIKH TKPIRSPNGV IITLYRQGRI DMYPQLPIGT PEKGKKPVYE
     DYYPKSRTGL GGLSFGVTRT SSVFRKDLSQ IFCPLIVDPN TMTAEIKTSI RIPENAFPTI
     TRVPGAMISF RYYVEVVMDI RGKLAGQDRF LPRLNMMSNN FYGNGKMNTA AEIQRGMTAS
     NVAGNILDTE QVRRDKSVIV CLFEIVVGSK DSSRGQRQDA SSLSDQSHQQ STSPDDLQEQ
     QSTPRHTRSA SQSPPPHNGY DPAGTSDWPD HPPPHSDYSP DSPPPMFIPP AQPEENVDEK
     TRLRRAEEML LPSEPPPHEG DVAGPSSAPH GLPPSAPVLS EDDSNYQPAN TRNNHNDFNP
     VNRNTSPSVS APSTDTITPT YCITNDHSPP SIPSGHPQAH AWPEAARNNA SLNNTVPQSR
     VQDDKQELER QRLLNEASSP GDYGYARIHE GDFSNNFEPS APALTEEDIF RPSCLGYTG
//