ID A0A0J8RAK9_COCIT Unreviewed; 585 AA.
AC A0A0J8RAK9;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 22-FEB-2023, entry version 25.
DE SubName: Full=Nuc-2 protein {ECO:0000313|EMBL:KMU82124.1};
GN ORFNames=CISG_09654 {ECO:0000313|EMBL:KMU82124.1};
OS Coccidioides immitis RMSCC 3703.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=454286 {ECO:0000313|EMBL:KMU82124.1, ECO:0000313|Proteomes:UP000054559};
RN [1] {ECO:0000313|Proteomes:UP000054559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 3703 {ECO:0000313|Proteomes:UP000054559};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; DS268215; KMU82124.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J8RAK9; -.
DR STRING; 454286.A0A0J8RAK9; -.
DR Proteomes; UP000054559; Unassembled WGS sequence.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR PANTHER; PTHR22958:SF23; DEPENDENT KINASE INHIBITOR PHO81, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06020)-RELATED; 1.
DR PANTHER; PTHR22958; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF03009; GDPD; 1.
DR SMART; SM00248; ANK; 3.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS51704; GP_PDE; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000054559}.
FT REPEAT 14..47
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 49..81
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 299..585
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
SQ SEQUENCE 585 AA; 65335 MW; 1A97E9071E348347 CRC64;
MLLEQNAKLL PDAEGIYPQH LVARSCRAPE VILLLKSHGA DLDQKDKLYQ WTPLFHAASE
GCVSCLRTLL DSGVDADTLD EKGFPAMYYA VWEGHLECMI LLWSRQTSSK LSQPSLNTLN
GPNFRDAASM TSPALAEPGG MDGDGIPDLS LPPPIIPLRR YGHNFLDNKT FLQICFEPAP
SEPILFYQAG RYAAARLIIS SKMSDLIPRN IMLPLQEDSR AISFQIDRLD NFALEFEIFP
TFGSKVIAKT VALPDLFTGG IRSSGSYCLP LFDPRLRPIG EMKFSFQVIK PYYGEPLEIT
HFATYWKATS SLDSDHNGQV TGSSLSGDYV QLFIQLTADN VPVLYPEFTV NHHGIEIPIC
HLTYEQFKLV GNERHAQMQS SESALLHSLD AMSIDDLAHV HRVLATSFLP LREVLGHLPT
NIHVNLCILY PSLADAKEFG FGPQTDVNVF ADSILAEVFH HARASKENDP YFMRSIVFTS
YNPDICIALN WKQPNFPVVL CNDLGQIRDL TRDSTSQPLI RCSGRASMSI KEAARIAQSN
NFMGLMCRSS LLNVMPALVE SIKEQNLFSW RTHPMSRERV DPVLG
//
