ID A0A0J8RQ42_COCIT Unreviewed; 296 AA.
AC A0A0J8RQ42;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Replication protein A 32 kDa subunit {ECO:0000313|EMBL:KMU87185.1};
GN ORFNames=CIHG_05126 {ECO:0000313|EMBL:KMU87185.1};
OS Coccidioides immitis H538.4.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=396776 {ECO:0000313|EMBL:KMU87185.1, ECO:0000313|Proteomes:UP000054563};
RN [1] {ECO:0000313|Proteomes:UP000054563}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H538.4 {ECO:0000313|Proteomes:UP000054563};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the replication factor A protein 2 family.
CC {ECO:0000256|ARBA:ARBA00007815}.
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DR EMBL; DS016996; KMU87185.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J8RQ42; -.
DR STRING; 396776.A0A0J8RQ42; -.
DR VEuPathDB; FungiDB:CIHG_05126; -.
DR eggNOG; KOG3108; Eukaryota.
DR Proteomes; UP000054563; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd04478; RPA2_DBD_D; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR040260; RFA2-like.
DR InterPro; IPR014646; Rfa2/RPA32.
DR InterPro; IPR014892; RPA_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR13989:SF16; REPLICATION PROTEIN A 32 KDA SUBUNIT; 1.
DR PANTHER; PTHR13989; REPLICATION PROTEIN A-RELATED; 1.
DR Pfam; PF08784; RPA_C; 1.
DR PIRSF; PIRSF036949; RPA32; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054563}.
FT DOMAIN 183..284
FT /note="Replication protein A C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08784"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 191..226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 296 AA; 32257 MW; 90FBD731DC566307 CRC64;
MEYGYGDQFP SGSYGQGGGG GGGGGEGGFM SEVGASQSGK TYNKSSLRPV TIKQLNDATQ
AYSDADFKID DTEVAQVSFV GQIRNISQLS TFMTYKLDDG TGEIEVKKWL DNEERHEGDA
MDTSDPTTGR TGKKELVVNG YAKVWGKLGS FSNNRRSVTA HVIRTLTNMD EYHCHFLEAT
AIHLYFKHGP PPSKDAADAS KAQTSGSGGA MRSDNSMAAG ERTLPPMSPM ARKLFNTLNN
TPQSREGLHL QHLASLMQAP VDNVEKAARE LNDLSLIYPT VDDYTWTIMD FKVDMQ
//
