ID A0A0J8S3H2_COCIT Unreviewed; 1093 AA.
AC A0A0J8S3H2;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Histone deacetylase HosB {ECO:0000313|EMBL:KMU91386.1};
GN ORFNames=CIHG_09131 {ECO:0000313|EMBL:KMU91386.1};
OS Coccidioides immitis H538.4.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=396776 {ECO:0000313|EMBL:KMU91386.1, ECO:0000313|Proteomes:UP000054563};
RN [1] {ECO:0000313|Proteomes:UP000054563}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H538.4 {ECO:0000313|Proteomes:UP000054563};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; DS017035; KMU91386.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J8S3H2; -.
DR STRING; 396776.A0A0J8S3H2; -.
DR VEuPathDB; FungiDB:CIHG_09131; -.
DR eggNOG; KOG1343; Eukaryota.
DR Proteomes; UP000054563; Unassembled WGS sequence.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR CDD; cd09998; HDAC_Hos3; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR47558; HISTONE DEACETYLASE HOS3; 1.
DR PANTHER; PTHR47558:SF1; HISTONE DEACETYLASE HOS3; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01270; HDASUPER.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054563}.
FT DOMAIN 270..603
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT REGION 1..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 741..824
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 845..925
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 942..1006
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..68
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..145
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 745..767
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 776..790
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 796..817
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 874..893
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 907..925
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 942..964
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 965..998
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1093 AA; 119217 MW; 7239B903160C0B02 CRC64;
MDGRKPPPAM APKQHAGSSG RQSTLTTNNE REQLVSSFNQ LSLAPQAALP RHSPSRTSSQ
SYRTLDKPQQ AQHDPLAHRS PVPRRTPSIN SLREDRRSST PSLKKRLSTA SLRSVQNSNG
VGSPRPSTSR RASHQFLSTP GSMMRPISPS VMSECPSPPP LPTASSIAAE HFEKELALHQ
STDLRSKTVV VLQDSCYGHR YSRPRTSKAG LESIVERPER LRAGVLGVAS AYVRMGKRWG
NHRCAPHPDL DLSSLPVPPF QILKTTRTLP LNSPAVTHVH GAKWMGELKM MCDAAESRLA
LNGKELVRPN SSGSDSSGSM PKLHEGDLYL CPESLNAFEG ALGGVCEAID TVFESDATRR
AFVCIRPPGH HCSSNFPSGF CWLNNVHVGI AHAAMTHGLT HAAIIDFDLH HGDGSQAIAW
EQNQRAISAS RNAPLHKKTR IGYFSLHDIN SYPCESGDEA KVMSASVCID NAHGQSVWNV
HLEPWKDAVE FWQLYNTKYA VLLDKARCFL RSCSQQLRDS PNSIHPKAAI FLSAGFDASE
WEGIGMQRHK VNVPTDFYAK FTSDINRLAE EEDLAVDGRV ISVLEGGYSD RALTSGIFSH
LSALADTRNV VVDDMDAQSR LASEMFSRLN LSDKASNAPS CDSTEEPILF DTIWWTGPML
EELEIIAQKP PPAPIRKPRE KGQPSFLAHT QASAAKAVTP VRERGVLFSH HATLDEPFSL
PEVDWALAAV ELSKAIIPTD RQTSSLKHAD LKGENARSKR ERHSLTGSTD LESVSERGHM
QLRERKPKAP VIPELQPGNS RSSSRSTRRT TIASSSDLAD GALPETPIES LDQTQVVVPQ
HSRKLSVTSS VASVGSAAPR NISLRKPREA SSRPVSRAQA STRPATSMGI NVQKQRAVGV
GDRSGSRKST PLDTTSAQSQ HGDVDHVSNG VKKLSLKLKV PTPEEHAARE AARIAEERNR
NMSKTAKKTP AAKPTKQTAG KSTSKTSRNA TISEAPRAES DTTDPRMIPL PSESTPVSST
ENSLAISAGS RTAANYRPPI FSFSAPYTIV TLRQTPNHSQ VGPSEKLTQR KTFLFHLDFC
HSLWPSRDSN TGS
//
