ID A0A0J8TGI2_COCIT Unreviewed; 813 AA.
AC A0A0J8TGI2;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 22-FEB-2023, entry version 25.
DE RecName: Full=DNA repair protein REV1 {ECO:0000256|ARBA:ARBA00020399};
GN ORFNames=CISG_03176 {ECO:0000313|EMBL:KMU72742.1};
OS Coccidioides immitis RMSCC 3703.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=454286 {ECO:0000313|EMBL:KMU72742.1, ECO:0000313|Proteomes:UP000054559};
RN [1] {ECO:0000313|Proteomes:UP000054559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 3703 {ECO:0000313|Proteomes:UP000054559};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
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DR EMBL; DS268128; KMU72742.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J8TGI2; -.
DR STRING; 454286.A0A0J8TGI2; -.
DR Proteomes; UP000054559; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
DR GO; GO:0070987; P:error-free translesion synthesis; IEA:UniProt.
DR GO; GO:0042276; P:error-prone translesion synthesis; IEA:InterPro.
DR CDD; cd17719; BRCT_Rev1; 1.
DR CDD; cd01701; PolY_Rev1; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 6.10.250.1490; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR012112; REV1.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR45990; DNA REPAIR PROTEIN REV1; 1.
DR PANTHER; PTHR45990:SF1; DNA REPAIR PROTEIN REV1; 1.
DR Pfam; PF16589; BRCT_2; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR PIRSF; PIRSF036573; REV1; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA synthesis {ECO:0000256|ARBA:ARBA00022634};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054559}.
FT DOMAIN 61..149
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 350..548
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT REGION 250..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 740..780
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..273
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 755..780
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 813 AA; 89772 MW; CDD8A61C92955FD3 CRC64;
MGSRLESGSN AVRKRIENHV FEDEEGEEYG ASSFGGFGEY FRRKKLKLQN LDAEIRSSSP
NNPPIFQGVV AHVNGYTQPS LNDLHRLIVS HGGAFLQYLD SKTAATHIIA SSLTPKKREE
FRKYRVVKPA WVVESINAGR LLPWNSFRVV DEGASQKVLK FSDNGQIVSQ TRTQSSSYRD
QTESSWYIAR LAPRYPDAKG FENSTIPTPS PKAVGDVGDS VFNTKASTNI AQQEQGFDDS
IPVENRTTSG DAEVAVHPED TDEPRQEPLE KTKDNMTPEE YNAQLLSNPH MRNSSGVNPD
FIRQYYRESR LHHLSTWKAE LKAKLQEATL AKVSSLRTPK KHVQGSRRYI LHVDFDSFFA
AVSIRKNPEL ADKPVAIAHG TGAGSEIASC NYPARAFGIQ NGMWMQGALQ MCPDLKVLPY
DFAAYEDASR KFYEAILDID GIVQSVSIDE ALVDITKLCL EAGGSEGKGI SEGSIWKEQA
KADEIAQTLR DSVKQKTGCD VSVGIGGNIL QAKLALRKAK PAGQFQLKPE VVLEFIGELT
VQQLPGVAYS LGAKLEELGV KFVKDIRELS RERLTSNLGP KTGAKLWDYA RGIDNADVGD
VAPRKSVSAE INWGIRFVTQ AQVEEFVQSL CDELHRRLME NGVKGKQLTM RIMRRALDAP
LGPPKHLGHG KCDMFNKSVL LGVATNSSEV LGKEAVSILR SFNFSPGNLR GLGVQMTKLE
SIKYDPSGGI HSSQRQLNFA PCSPQERRPS QDLDEITTPS KTESYVSVQT APELNDESQR
PMNITGTQFI MPSQANSQVL SELPGDIRSK LSL
//
