ID A0A0J9U4D8_FUSO4 Unreviewed; 608 AA.
AC A0A0J9U4D8;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 28-JUN-2023, entry version 17.
DE RecName: Full=DH domain-containing protein {ECO:0000259|PROSITE:PS50010};
GN ORFNames=FOXG_17809 {ECO:0000313|EMBL:KNA93722.1};
OS Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935
OS / NRRL 34936) (Fusarium vascular wilt of tomato).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=426428 {ECO:0000313|EMBL:KNA93722.1, ECO:0000313|Proteomes:UP000009097};
RN [1] {ECO:0000313|EMBL:KNA93722.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=4287 {ECO:0000313|EMBL:KNA93722.1};
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Ma L.-J., Jaffe D.,
RA Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.,
RA Brockman W., MacCallum I.A., Young S., LaButti K., DeCaprio D.,
RA Crawford M., Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C.,
RA Larson L., White J., O'Leary S., Kodira C., Zeng Q., Yandava C.,
RA Alvarado L., Kistler C., Shim W.-B., Kang S., Woloshuk C.;
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KNA93722.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4287 {ECO:0000313|EMBL:KNA93722.1};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
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DR EMBL; DS231696; KNA93722.1; -; Genomic_DNA.
DR RefSeq; XP_018231768.1; XM_018397796.1.
DR AlphaFoldDB; A0A0J9U4D8; -.
DR GeneID; 28958515; -.
DR KEGG; fox:FOXG_17809; -.
DR VEuPathDB; FungiDB:FOXG_17809; -.
DR OrthoDB; 24739at2759; -.
DR Proteomes; UP000009097; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR PANTHER; PTHR45818; PROTEIN VAV; 1.
DR PANTHER; PTHR45818:SF3; PROTEIN VAV; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009097}.
FT DOMAIN 1..148
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 431..509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 493..508
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 608 AA; 68185 MW; 5B0E90C7693978A1 CRC64;
MAPGDQGSLQ LLEKEPGVLS EPQVAADAAK IFRKRMHRFF MYKEYGAKYE MMIKDATSAL
ENLPEWELHQ KGLEAFAFTM ESSPSSDSRK ARTIGDLLVK PIQRICKYPL LFAELLRCTP
VIDCPNSHME VETTLMRLRE ATAEINRSTE DNLMKSILEK TWLLQDRIVF PNRRLDAHSK
NQVRSFGHIQ LCGVLHVCWQ SPAGVDGQYM ICLLYKDVLC LASGGKFEPI YKILACIDVH
CSAVEDADNG RGLQCHLAPF SWKLVFESDH QLYEVVMTAC TSREENEWRT RLQQPLCQEP
VGRSPGLQIF LSLDIQSLGT VFGRPGSIAR SLSTHQASVG SSEPCHVILK NTSTMKSSSG
TSSRAGLHRS QSLLSTKVRT PVLVPSRSER ARLEVLLSDV WSQDVLPLPS MTNIARNEQM
IRRSASTVMR KLSVSSMTKR SGSLSRRMIE DPSSEDQTRQ TSFSSDSGFD IFDKAGREES
SYSYASKGSA LPETRELSEE DDHVSDMSPR LELTQISELK PLDLIEIISD KQLQSEAENT
SALQDCITNR LQTNSPPNDS RTATLSVAKE NLSRLADSTA IQSTDVPWEK EKSSKNEKKC
TGIRRFFR
//
