ID A0A0J9U7T2_FUSO4 Unreviewed; 779 AA.
AC A0A0J9U7T2;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=IQ domain-containing protein containing GTPase activating protein {ECO:0000313|EMBL:KNA94882.1};
GN ORFNames=FOXG_00703 {ECO:0000313|EMBL:KNA94882.1};
OS Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935
OS / NRRL 34936) (Fusarium vascular wilt of tomato).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=426428 {ECO:0000313|EMBL:KNA94882.1, ECO:0000313|Proteomes:UP000009097};
RN [1] {ECO:0000313|EMBL:KNA94882.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=4287 {ECO:0000313|EMBL:KNA94882.1};
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Ma L.-J., Jaffe D.,
RA Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.,
RA Brockman W., MacCallum I.A., Young S., LaButti K., DeCaprio D.,
RA Crawford M., Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C.,
RA Larson L., White J., O'Leary S., Kodira C., Zeng Q., Yandava C.,
RA Alvarado L., Kistler C., Shim W.-B., Kang S., Woloshuk C.;
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KNA94882.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4287 {ECO:0000313|EMBL:KNA94882.1};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
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DR EMBL; DS231696; KNA94882.1; -; Genomic_DNA.
DR RefSeq; XP_018232928.1; XM_018377239.1.
DR AlphaFoldDB; A0A0J9U7T2; -.
DR GeneID; 28943003; -.
DR KEGG; fox:FOXG_00703; -.
DR VEuPathDB; FungiDB:FOXG_00703; -.
DR OrthoDB; 24454at2759; -.
DR Proteomes; UP000009097; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR CDD; cd05132; RasGAP_GAPA; 1.
DR InterPro; IPR000593; RasGAP_C.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR14149:SF17; GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR14149; RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF; 1.
DR Pfam; PF00616; RasGAP; 1.
DR Pfam; PF03836; RasGAP_C; 1.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF143885; RGC domain-like; 1.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000009097}.
FT DOMAIN 185..401
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 58..85
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 779 AA; 89448 MW; 9ABD66D0396839FC CRC64;
MSIMLQTPSR ASTASSSSFQ PISRQNTMSS YDGSRSARQS KRYSMSALYM SISANEGDLQ
IEDELAKAQK ALRDLKSKIS SQSKKNFVLE KDVRYLDSRI ALLIQNRMAL EEQNEVASHL
EDALEMQQGV FPNDDKTQKY GNLLFLLQSE PRHIAHLCRL VSMSEIDSLL QTVMFTIYGN
QYESREEHLL LTMFQSVLTY QFDNTPDYSS LLRANTPVSR MMTTYTRRGP GQSFLKSVLA
DRINGLIELK DLDLEINPLK VYERMIEQIE EDTGQLPPHL PKGITGEQAA ENPQVQAIIE
PRLTMLTEIA NGFLTTIIEG LEEAPYGIRW ICKQIRSLTK RKYPDANDQV ICTLIGGFFF
LRFINPAIVT PKSYMLIDGT PAERPRRTLT YIAKMLQNLA NKPSYAKEPY MAKLQPFIHQ
NKDRINKFML DLCEVQDFYE SLEMDNYVAL SKKDLELEIT LNEVYAMHSL LDKHHDELCK
DDNSHLAIIM SELGSSPPQL PRKENRVINL PLFSRWESAI GDLTAALDIT QEEVYFMEAK
SIFVQVMRSI PATSGVARRP LRLERIADAA ATNRSDAVMV RKGIRAMELL SQLQELRVID
KADQFSLLRD EVEQELQHLG SLKEGVITET QKLQEVYKTI RDHNVYLNGQ LETYKSYLHN
VRSQSEGTKR KQQKQQVLGP YKFTHQQLEK EGVIQKSNVP DNRRANIYFN FTSPLPGTFV
ISLHYKGRNR GLLELDLKLD DLLEMQKDNQ DDLDLEYVQF NVPKVLALLN KRFARKKGW
//
