ID A0A0J9VAT9_FUSO4 Unreviewed; 423 AA.
AC A0A0J9VAT9;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Vacuolar protein 8 {ECO:0000256|ARBA:ARBA00026209, ECO:0000256|RuleBase:RU369097};
GN ORFNames=FOXG_09067 {ECO:0000313|EMBL:KNB08061.1};
OS Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935
OS / NRRL 34936) (Fusarium vascular wilt of tomato).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=426428 {ECO:0000313|EMBL:KNB08061.1, ECO:0000313|Proteomes:UP000009097};
RN [1] {ECO:0000313|EMBL:KNB08061.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=4287 {ECO:0000313|EMBL:KNB08061.1};
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Ma L.-J., Jaffe D.,
RA Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.,
RA Brockman W., MacCallum I.A., Young S., LaButti K., DeCaprio D.,
RA Crawford M., Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C.,
RA Larson L., White J., O'Leary S., Kodira C., Zeng Q., Yandava C.,
RA Alvarado L., Kistler C., Shim W.-B., Kang S., Woloshuk C.;
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KNB08061.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4287 {ECO:0000313|EMBL:KNB08061.1};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
CC -!- FUNCTION: Functions in both vacuole inheritance and protein targeting
CC from the cytoplasm to vacuole. {ECO:0000256|ARBA:ARBA00024821,
CC ECO:0000256|RuleBase:RU369097}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004635}; Lipid-
CC anchor {ECO:0000256|ARBA:ARBA00004635}. Vacuole membrane
CC {ECO:0000256|ARBA:ARBA00004592, ECO:0000256|RuleBase:RU369097}; Lipid-
CC anchor {ECO:0000256|ARBA:ARBA00004592, ECO:0000256|RuleBase:RU369097}.
CC -!- SIMILARITY: Belongs to the beta-catenin family.
CC {ECO:0000256|ARBA:ARBA00005462, ECO:0000256|RuleBase:RU369097}.
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DR EMBL; DS231706; KNB08061.1; -; Genomic_DNA.
DR RefSeq; XP_018246106.1; XM_018388101.1.
DR AlphaFoldDB; A0A0J9VAT9; -.
DR GeneID; 28950651; -.
DR VEuPathDB; FungiDB:FOXG_09067; -.
DR OrthoDB; 2721872at2759; -.
DR Proteomes; UP000009097; Unassembled WGS sequence.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043495; F:protein-membrane adaptor activity; IEA:InterPro.
DR GO; GO:0071562; P:nucleus-vacuole junction assembly; IEA:InterPro.
DR GO; GO:0000011; P:vacuole inheritance; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR045156; Vac8.
DR PANTHER; PTHR47249; VACUOLAR PROTEIN 8; 1.
DR PANTHER; PTHR47249:SF1; VACUOLAR PROTEIN 8; 1.
DR Pfam; PF00514; Arm; 5.
DR SMART; SM00185; ARM; 7.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50176; ARM_REPEAT; 6.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Membrane {ECO:0000256|RuleBase:RU369097};
KW Reference proteome {ECO:0000313|Proteomes:UP000009097};
KW Vacuole {ECO:0000256|ARBA:ARBA00022554, ECO:0000256|RuleBase:RU369097}.
FT REPEAT 1..34
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 33..75
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 74..114
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 117..159
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 158..200
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 199..242
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ SEQUENCE 423 AA; 45933 MW; 7F1F9FA61F6CA95A CRC64;
MMSPNVEVQC NAVGCITNLA THEENKAKIA RSGALGPLTR LAKSRDMRVQ RNATGALLNM
THSDENRQQL VNAGAIPVLV QLLSSPDVDV QYYCTTALSN IAVDASNRRK LAQSEPKLVQ
SLVNLMDSTS PKVQCQAALA LRNLASDEKY QLDIVRANGL HPLLRLLQSS YLPLILSAVA
CIRNISIHPL NESPIIETNF LKPLVDLLGS TDNEEIQCHA ISTLRNLAAS SDRNKALVLD
AGAVQKCKQL VLDVPITVQS EMTAAIAVLA LSDDLKSHLL NLGVCGVLIP LTHSPSIEVQ
GNSAAALGNL SSKVGDYSIF VQNWTEPQGG IHGYLCRFLQ SGDATFQHIA VWTLLQLFES
EDKTLIGLIG KAEDIIEHIR SIANRQIETD NEFEDEDEGE VVNLAQRCLE LLGQSMSKAH
IEG
//
