ID A0A0J9WPT0_FUSO4 Unreviewed; 1286 AA.
AC A0A0J9WPT0;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=5-oxoprolinase (ATP-hydrolysing) {ECO:0008006|Google:ProtNLM};
GN ORFNames=FOXG_10118 {ECO:0000313|EMBL:KNB09567.1};
OS Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935
OS / NRRL 34936) (Fusarium vascular wilt of tomato).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=426428 {ECO:0000313|EMBL:KNB09567.1, ECO:0000313|Proteomes:UP000009097};
RN [1] {ECO:0000313|EMBL:KNB09567.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=4287 {ECO:0000313|EMBL:KNB09567.1};
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Ma L.-J., Jaffe D.,
RA Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.,
RA Brockman W., MacCallum I.A., Young S., LaButti K., DeCaprio D.,
RA Crawford M., Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C.,
RA Larson L., White J., O'Leary S., Kodira C., Zeng Q., Yandava C.,
RA Alvarado L., Kistler C., Shim W.-B., Kang S., Woloshuk C.;
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KNB09567.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4287 {ECO:0000313|EMBL:KNB09567.1};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
CC -!- SIMILARITY: Belongs to the oxoprolinase family.
CC {ECO:0000256|ARBA:ARBA00010403}.
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DR EMBL; DS231707; KNB09567.1; -; Genomic_DNA.
DR RefSeq; XP_018247612.1; XM_018389358.1.
DR GeneID; 28951616; -.
DR KEGG; fox:FOXG_10118; -.
DR VEuPathDB; FungiDB:FOXG_10118; -.
DR OrthoDB; 674at2759; -.
DR Proteomes; UP000009097; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR InterPro; IPR049517; ACX-like_C.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR003692; Hydantoinase_B.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR Pfam; PF19278; Hydant_A_C; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
DR Pfam; PF02538; Hydantoinase_B; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009097}.
FT DOMAIN 5..219
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 239..529
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 540..705
FT /note="Acetophenone carboxylase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19278"
FT DOMAIN 741..1269
FT /note="Hydantoinase B/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF02538"
SQ SEQUENCE 1286 AA; 139679 MW; FDE4772BC8140BD8 CRC64;
MGDIRVSIDR GGTFCDVIAT GADGNDPFIF KLLSEDPSNY PDAPAEAIRR VLEKYEGKTI
PVGEKLDASR IASCRIGTTV ATNALLTGNG EKFAFATTKG FKDVCVIGDQ SRPELFNLEI
RKPTALHSSV IEIDERVTIE DYDLNPHKQK TVNIENDANL VKTPSGEVIR ILKRPDEKVV
RQQLEALLEQ GYTSLAVCFM HAYIFPDHEK MVARIAKKVG FQFVTISSET SPAINFLRRS
NSTCSEAYLY PIIRRYINNF QAGFKISPQR VEFMCSDGGL KQADKFRGNE ALLSGPAGGV
VGTAKCFDVD EGTPVIGFDM GGTSTDVSRY DGKYDFLQQT SIAGRTINLS MLNIATVAAG
GGSILFARNG FLSVGPESAG AHPGPSCYRK GGPLTVTDAN LFLGRLVISS FPAIFGESGD
QEIDTEIVAR KFEKITQDFN RQTSQDLTRE EVASGFLNIA NETMSRPIRN ATEARGYAPE
SHNLVSFGGA GGQHACAIAD KLGIKRVIIH KLSSLLSAHG IAHAELQYEM FEPFAAELDI
KAMKGVESLL LTLKDKVTKE LVSQKVSEES LVFDEALVLK YFGTDTNLSI SKPADGDYAA
AFTALHLREF AFSMNRPIII ESVKVRGSGS TGAPSHETSA CKEMASRKRK LFSDSAVRQR
VYLDGSWQET RVFKLDDIPE GSLINGPAII IDETQTILVE SLFQAHILVN YVVLEKIASE
EQSLKCSISR TLSTSKDTLS PIQLSVFAHR FMAIAEQMGN TLQRTSISSS IKERLDFSCA
IFSPEGKLVA NAPHIPIHLG SMQFAVQAQH RHWSGKLKPG DVLLTNHPSW GGTHLPDLTV
VTPVFVGDQI AFYVASRGHH TDIGGMGITS MMPESRSLWE EGIIVPSMKI VSSGEFLESE
VRAAFEKVGT YPGCSATRRI QDNISDLKAQ TSANQRGITL LQKLCNEYSL EVVHKYMTGI
QDNAELAVRG FFKKLAHEHP GPLSATDYLD DGTAMKVRIS IDKDTGSAIY NFAGSGPQMW
GNYNCPISIT HSAIIYSIRC LVNLEIPLNE GCLAPCDIRV PVGSILNPTP TVAICGSTLA
SQRVIDLVLR AFGRFGASQG CANALGWGMG GKNPVTGKTE PGWNYGESIG GGVGAGEGYN
GASGVHVHST NTRQTDSEVI EKRTAVLVRR YGIREGSGGK GRWRGGDGII REIEARANLK
FSILSDRRVY RPYGMAGGYG GQKGENLAFK FNEQHEMEAI NLGGKAIVHL VPGEYIQINT
PGGGGYGTPD DEEVDPGFNN FHKAFT
//
