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Database: UniProt
Entry: A0A0J9XLD9_BRUMA
LinkDB: A0A0J9XLD9_BRUMA
Original site: A0A0J9XLD9_BRUMA 
ID   A0A0J9XLD9_BRUMA        Unreviewed;       430 AA.
AC   A0A0J9XLD9;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   05-JUL-2017, entry version 16.
DE   SubName: Full=BMA-SHK-1, isoform e {ECO:0000313|EMBL:CDP90796.1};
GN   Name=bma-shk-1 {ECO:0000313|WormBase:Bm7671e};
GN   Synonyms=Bma-shk-1 {ECO:0000313|EMBL:CDP90796.1};
GN   ORFNames=Bm7671 {ECO:0000313|WormBase:Bm7671e}, BM_Bm7671
GN   {ECO:0000313|EMBL:CDP90796.1};
OS   Brugia malayi (Filarial nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Spirurida;
OC   Filarioidea; Onchocercidae; Brugia.
OX   NCBI_TaxID=6279 {ECO:0000313|EMBL:CDP90796.1};
RN   [1] {ECO:0000313|EMBL:CDP90796.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=FR3 {ECO:0000313|EMBL:CDP90796.1};
RX   PubMed=17885136; DOI=10.1126/science.1145406;
RA   Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J.,
RA   Allen J.E., Delcher A.L., Guiliano D.B., Miranda-Saavedra D.,
RA   Angiuoli S.V., Creasy T., Amedeo P., Haas B., El-Sayed N.M.,
RA   Wortman J.R., Feldblyum T., Tallon L., Schatz M., Shumway M., Koo H.,
RA   Salzberg S.L., Schobel S., Pertea M., Pop M., White O., Barton G.J.,
RA   Carlow C.K., Crawford M.J., Daub J., Dimmic M.W., Estes C.F.,
RA   Foster J.M., Ganatra M., Gregory W.F., Johnson N.M., Jin J.,
RA   Komuniecki R., Korf I., Kumar S., Laney S., Li B.W., Li W.,
RA   Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA   McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA   Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA   Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA   Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA   Blaxter M.L., Scott A.L.;
RT   "Draft genome of the filarial nematode parasite Brugia malayi.";
RL   Science 317:1756-1760(2007).
RN   [2] {ECO:0000313|EMBL:CDP90796.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=FR3 {ECO:0000313|EMBL:CDP90796.1};
RA   Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA   Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL   Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
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DR   EMBL; LN854750; CDP90796.1; -; Genomic_DNA.
DR   EnsemblMetazoa; Bm7671e; Bm7671e; WBGene00227932.
DR   WormBase; Bm7671e; BM45061; WBGene00227932; Bma-shk-1.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR   InterPro; IPR003972; K_chnl_volt-dep_Kv1.
DR   InterPro; IPR011333; SKP1/BTB/POZ.
DR   InterPro; IPR003131; T1-type_BTB.
DR   InterPro; IPR028325; VG_K_chnl.
DR   PANTHER; PTHR11537; PTHR11537; 1.
DR   Pfam; PF02214; BTB_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01491; KVCHANNEL.
DR   PRINTS; PR01496; SHAKERCHANEL.
DR   SUPFAM; SSF54695; SSF54695; 1.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00788393, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00793138,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00789957,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268};
KW   Voltage-gated channel {ECO:0000256|SAAS:SAAS00091688}.
FT   TRANSMEM    172    194       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    214    234       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    246    265       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    316    335       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    347    364       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    376    399       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       47    138       BTB_2. {ECO:0000259|Pfam:PF02214}.
FT   DOMAIN      175    406       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   430 AA;  49629 MW;  EB131B6D63377D13 CRC64;
     MDTPSNREVS DEKPNNGSIF PMITEEEPNN IMFNDTSSAK QLERNLITIN VSGLRFQTYE
     STLERYPLTL LGNSFKRNRF WDPKNEEYFF DRHRTSFESI LYAYQSGGIM KRPESVPIDM
     FVKELKFFEM GEELLEKFWI SEGYEKPKEI QMPQNVLQRQ LWELVEYPDS SLFARIFALL
     SIFVISISII SFCLETLPSM KENPGDVRDW SNPFFYIELF CIIWFTIELL LRFISCPNKF
     SFLRSVLNII DFVAIAPFFG NLMWMDSTKS SSSMSFAVLR VLRLVRVFRI FKLSRHSVGL
     QILGKTFRAS IQEFCLLIFF MVIALVLFSS GVYFAEQNEP NTKFTSIPAS FWFVLVTMTT
     VGYGDLTPTG VYGKLVGGLC ALIGVLTLAL PVPIIVANFK HFYRQETRLA QMRASAEEDE
     TNSEHSSKSP
//
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