ID A0A0J9XLH7_BRUMA Unreviewed; 572 AA.
AC A0A0J9XLH7;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=ATP-dependent Clp protease, ATP-binding subunit, putative {ECO:0000313|WBParaSite:Bm4855.1};
DE SubName: Full=Bm4855 {ECO:0000313|EMBL:CDP90941.1};
GN ORFNames=Bm4855 {ECO:0000313|EMBL:CDP90941.1,
GN ECO:0000313|WBParaSite:Bm4855.1, ECO:0000313|WormBase:Bm4855},
GN BM_Bm4855 {ECO:0000313|EMBL:CDP90941.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CDP90941.1};
RN [1] {ECO:0000313|EMBL:CDP90941.1, ECO:0000313|Proteomes:UP000006672}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP90941.1,
RC ECO:0000313|Proteomes:UP000006672};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CDP90941.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP90941.1};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:Bm4855.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2019) to UniProtKB.
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DR EMBL; LN855269; CDP90941.1; -; Genomic_DNA.
DR STRING; 6279.A0A0J9XLH7; -.
DR EnsemblMetazoa; Bm4855.1; Bm4855.1; WBGene00225116.
DR WBParaSite; Bm4855.1; Bm4855.1; WBGene00225116.
DR WormBase; Bm4855; BM32611; WBGene00225116; -.
DR OMA; AFRSKPC; -.
DR OrthoDB; 452393at2759; -.
DR Proteomes; UP000006672; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd19497; RecA-like_ClpX; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR48102:SF7; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR48102; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006672}.
FT DOMAIN 254..407
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 470..562
FT /note="Clp ATPase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01086"
FT REGION 189..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 572 AA; 62892 MW; 2579F59902E6CEA8 CRC64;
MVCPSSAVVI ARRQCQSFLI VRTVRHITKS GGSSNDSGSG TDDWENNNTS SEHILFRQRI
PLHASVPLTG KHVTTRWNIW RTSSCNSRCD ECGKPLKNIP SSTPSSRYLI CENCRRLFSC
GPPDEDDEKG SILKASEADK KPPYPKEIYG FLNKYIIGQE QAKKTLSVGV YQHYLRLYHN
IENNVSSPAM NNAEGNRPRT GASSSGVLYQ EDYSRTSRAD IRFFSEVTAP QQKHRIGSPV
FRPLPENDVP IRLEKSNILL LGPSGVGKTF ITQTLARILD VPIALCDCTS MTQAGYVGED
VESVVQKLVQ NAGGNVERAQ QGIVFLDEID KIAAAHNVQS HAFRDVSGEG VQHALLKLVE
GTLVNVKSSR KSMSTQQDFV QVDTTDILFV ASGAFTALDR IVGKRLDKKT LGLGAKSGMQ
RITDDDKLEA AISKKRDDLL RQADQGDLIS FGIVPELVGR FPVIVPFHSL DKGMLVRVLT
EPTNSLLAQK KLEFAMDGAD LSFSSDALDE IAALALERKT GARALRSIVE KVLLEAKFTV
PGSDIESVHI NRECVQGKAD YVYTRRAQQA TG
//
