ID A0A0J9XQX8_BRUMA Unreviewed; 1015 AA.
AC A0A0J9XQX8;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=BMA-ZFP-1, isoform a {ECO:0000313|WBParaSite:Bm4379a.1};
DE SubName: Full=BMA-ZFP-1, isoform c {ECO:0000313|EMBL:CDP93258.1};
GN Name=bma-zfp-1 {ECO:0000313|WormBase:Bm4379c};
GN Synonyms=Bm1_18910 {ECO:0000313|WBParaSite:Bm4379a.1}, Bma-zfp-1
GN {ECO:0000313|EMBL:CDP93258.1};
GN ORFNames=Bm4379 {ECO:0000313|WormBase:Bm4379c}, BM_Bm4379
GN {ECO:0000313|EMBL:CDP93258.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CDP93258.1};
RN [1] {ECO:0000313|EMBL:CDP93258.1, ECO:0000313|Proteomes:UP000006672}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP93258.1,
RC ECO:0000313|Proteomes:UP000006672};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CDP93258.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP93258.1};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:Bm4379a.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2022) to UniProtKB.
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DR EMBL; LN856867; CDP93258.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J9XQX8; -.
DR EnsemblMetazoa; Bm4379a.1; Bm4379a.1; WBGene00224640.
DR WBParaSite; Bm4379a.1; Bm4379a.1; WBGene00224640.
DR WormBase; Bm4379c; BM37979; WBGene00224640; Bma-zfp-1.
DR OrthoDB; 2882280at2759; -.
DR Proteomes; UP000006672; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd20901; CC_AF10; 1.
DR CDD; cd15574; PHD_AF10_AF17; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR049773; AF10-like_CC.
DR InterPro; IPR049781; AF10/AF17_PHD.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF162; ALHAMBRA, ISOFORM P; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000006672};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 2..54
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 73..191
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT REGION 239..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 332..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 438..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 488..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 686..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 991..1015
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..354
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..456
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..513
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 702..724
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1015 AA; 105253 MW; 6210566E1E6CB299 CRC64;
MLGGCCVCAD ENGWESNPLV YCDGPNCEVA VHQGCYGIVE VPEGEWYCAK CADFIAHSQY
NGNNGDVGEV REIPRCKLCP FGHGALKRTD NDEWAHVICA LYIPEVRFGD VHSMDPVILS
DVPLERFQQQ CYLCMERGEE KRAYLGACMP CNKPGCKKCF HVTCAQAEGL LCEEGGGSKN
VKYCGYCAAH AKKAISDPLI KIIPPYRHRA ESSCSSGSGG GGGVQRAVTP KLGTGNICSG
DNSGQTSSTS SPHFNSSELL QNTSIGSSYG SVKLATTTSS SGTATSFPSS LRAEGPAMLV
DALYRTSLPP PTVDRAMLNA VMSQSLAVHS MRDDACSPPM SSGRSSTAHS TPPPVPASVS
LKKDHSVYEL PSSSNATISL PSNVALLGAS AQKSELSTDI AEEKDLNGTL ISQLEIKLQS
RTNYGPIDNG SVASVGNKTV KRKAAEAAER PKRPRNNKAC KSMKALLESV GPLISETVSD
FQRERLNERD SNMTTAATSH STAPSTSGEH EITTCTDSAS TSTAHCTVVT CSLTSTQQQQ
PSTSTVTTST FVGVPLIRAQ PKAVVSPDAG AAVIAVDRTH VASSLPSTSG AAGATTSLCP
MSQQSVAFPQ SMEELLERQW EQGSHFLMSH APFDIAQLLS CLHELKMENI RLEETLSQLA
RRRDHLLALN TRLSLSLASG SSLGLGTSPH HSPRISAAGS GGSIPLASTS SMQPNSGISS
TQCTTQSTSS ASISSLPSIV PLPPTTVCGQ QQQQQSLQAA AGSAVISFLN PFCSTLPPII
DDSLNQLRSL ANNGSVITNR SSHTPQAAVA AAAAAAAVAA AGQLAGTTAG TENRQTPVAS
TAGIASVQQA SLPSSRIPSA ASANTGISTP LLANFTNAQL ATSMSSTAAV TNALDLFGGS
QNNAHLTLTS ERQQMAAAAI AAAAAANALG GNFVAPRTPT HSSTAVSGTS SIGQLASTEL
LAQYALLAQQ QLLHQQAAVA ALSARYGSQV ISSSSTSPHS TSSNSQLSSN PHSGK
//
