ID A0A0J9XRN2_BRUMA Unreviewed; 677 AA.
AC A0A0J9XRN2;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Bm3343 {ECO:0000313|EMBL:CDP94180.1, ECO:0000313|WBParaSite:Bm3343d.2};
DE SubName: Full=Bm3343, isoform b {ECO:0000313|WBParaSite:Bm3343d.1};
GN Name=Bm1_32315 {ECO:0000313|WBParaSite:Bm3343d.1};
GN ORFNames=Bm3343 {ECO:0000313|WBParaSite:Bm3343d.2,
GN ECO:0000313|WormBase:Bm3343a}, BM_Bm3343
GN {ECO:0000313|EMBL:CDP94180.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CDP94180.1};
RN [1] {ECO:0000313|EMBL:CDP94180.1, ECO:0000313|Proteomes:UP000006672}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP94180.1,
RC ECO:0000313|Proteomes:UP000006672};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CDP94180.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP94180.1};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:Bm3343d.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2022) to UniProtKB.
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DR EMBL; LN856924; CDP94180.1; -; Genomic_DNA.
DR EnsemblMetazoa; Bm3343d.1; Bm3343d.1; WBGene00223604.
DR EnsemblMetazoa; Bm3343d.2; Bm3343d.2; WBGene00223604.
DR WBParaSite; Bm3343d.1; Bm3343d.1; WBGene00223604.
DR WBParaSite; Bm3343d.2; Bm3343d.2; WBGene00223604.
DR WormBase; Bm3343a; BM33518; WBGene00223604; -.
DR Proteomes; UP000006672; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0019205; F:nucleobase-containing compound kinase activity; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01428; ADK; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_00235; Adenylate_kinase_Adk; 1.
DR InterPro; IPR000850; Adenylat/UMP-CMP_kin.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23359:SF111; ADENYLATE KINASE ISOENZYME 5-LIKE PROTEIN; 1.
DR PANTHER; PTHR23359; NUCLEOTIDE KINASE; 1.
DR Pfam; PF00406; ADK; 2.
DR PRINTS; PR00094; ADENYLTKNASE.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Reference proteome {ECO:0000313|Proteomes:UP000006672};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 237..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 341..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 655..677
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..450
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 663..677
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 677 AA; 74581 MW; 1179E791AA7D8DB4 CRC64;
MQTAEAASIP DVPIVLFMGG PGGGKTRHAA RVQEALNKFG LVHICMPDMI RVAIAKYQNS
NLEWKEAAQR YQRGELIPNN LALGLVKAEM SKHQGAKAFF LEGFPREARQ VESFEREVKP
VNMAMILDYD EITLRHHMES RGLDAEIIDA KIREFKLKTL PSAKYFDDQR LLHLIPGEQT
DQWIFERMKL LIQRAMELGV PVTTSKVASR AESPLQRPDA VATVAEAVAI VEAAVATAQT
SENRSRSPTK IEVEENETKA DPILSSATGT EGEPAATLVL NSPVTARDVT NTTTSAFEKA
TSETISEKDK LLTASKRQIS RKGNATNESK LAEVRADSAI TNTEVRERSQ ISGITSESIT
QPAPVTPVST NNAPNVEGSS QSSRQSTKSY TKRTLSKISR TVSQTSKSSE TSRRSAHSVK
SESQSAQSIK SETQLIGGPS PDSKSNVSAV DNRFPPGLPN NASAIVIVGP PGSNKAEISK
RIAVRYDGFM YLSMGDLLRK EVQANADDQL WQRIGKKMDA GEAVPTKICR ELLYSKIYDE
DNISSGYVIE GYPRTKNQAI DFENQIDRLV SVILIDCTED FCIETIKKRK KEGIVVRTDD
NPEVINARLQ MFKQNTLPML KYFDDKGKLK VVDGDNNLEK IFEEIVEELD STILAKDPKC
GGSQSLSEES QKKIAGQ
//
