ID A0A0J9Y8J0_BRUMA Unreviewed; 918 AA.
AC A0A0J9Y8J0;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Bm9007 {ECO:0000313|EMBL:CDQ04514.2};
DE Flags: Fragment;
GN Name=bma-mup-4 {ECO:0000313|WormBase:Bm9007};
GN ORFNames=Bm9007 {ECO:0000313|EMBL:CDQ04514.2,
GN ECO:0000313|WormBase:Bm9007}, BM_Bm9007 {ECO:0000313|EMBL:CDQ04514.2};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CDQ04514.2};
RN [1] {ECO:0000313|EMBL:CDQ04514.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDQ04514.2};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CDQ04514.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDQ04514.2};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; LN856810; CDQ04514.2; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J9Y8J0; -.
DR WormBase; Bm9007; BM40535; WBGene00229268; Bma-mup-4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 5.
DR Gene3D; 2.10.25.10; Laminin; 6.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR000082; SEA_dom.
DR InterPro; IPR036364; SEA_dom_sf.
DR PANTHER; PTHR24039; FIBRILLIN-RELATED; 1.
DR PANTHER; PTHR24039:SF40; TRANSMEMBRANE MATRIX RECEPTOR MUP-4; 1.
DR Pfam; PF07645; EGF_CA; 5.
DR Pfam; PF01390; SEA; 1.
DR SMART; SM00181; EGF; 10.
DR SMART; SM00179; EGF_CA; 7.
DR SMART; SM00200; SEA; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 4.
DR SUPFAM; SSF82671; SEA domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 5.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 8.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS50024; SEA; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Membrane {ECO:0000256|SAM:Phobius};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 664..687
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 15..62
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 64..103
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 162..201
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 212..251
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 260..299
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 348..473
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT DOMAIN 520..557
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 576..614
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 621..657
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 814..850
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 889..918
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 821..850
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 893..909
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 628..645
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 647..656
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CDQ04514.2"
SQ SEQUENCE 918 AA; 101960 MW; 39F5616B4F48755D CRC64;
SPNPQHFGGT YCKPMINECA NESLNTCNKN AICIDTMDGY KCQCKDGFID HDEMRNPGRI
CQQENRLCIT NQNDCDKHAK CIEKGTNEYI CVCEPDYIDK SPEPSKPGRV CLERICSNPS
KHDCHPAASC TEVAKPERYT CSCRNGYSDM DLLRPGRICK ELVNECLNSS LNDCDPAATC
TDLKEGYTCT CPPNSKDISP NSQKPGRKCS ILVNECTNSH LNNCSRFADC IDREDGYECV
CKTGYRDGNP AKPGTDCKLI VNECQSSNLN NCDKNAECID TEEGYQCKCI PPYIDQNPSQ
PGTVCRKKGI PCGDTACQEE LGEICSENQL CICPPGQKRS GPEKKCRPVE SWSLPLLVIR
QNTEELNYND NLRNPQSDQY KELVSAFEKG IAESYANTSL KNGFVVAEVN EIARPSDFIK
QWDKGILYNF TVNFVRGSVA SPESVFTELL QYIAHRNNFE VGKSKQFISP YQANPFDNCY
KSDCHPDAKC TATPTGYRCE CIKPFVNAAP PGKLPGSVCH IDYCSDVNFC PANATCQNGE
REAQCVCKEG YVDIRPSLSQ NQPNYPEMVH CVLLQDVNEC ALGLTNCSAV AVCTDLRIGY
ECHCPNGYLD GNPSEPGRIC AAQLCGLCNG HGDCIYNEAT KNVTCSCVGG YTGEFCEIEP
SKTLLLLFLI LAVLLLLLSL CLCMYFCSRL RCFRRKPETS IGSGREILSS DYYSIPRAKL
KRREVDDTAP AEVSSRQLQR YLDDGGSISG ESSGSSVQFE RRVITDITTH EIKKTIYHDP
ETGQAIYEVT ATASSSAGDG GHSQFLRPPI EIESEQHAGE QYPRSESTSR IDGSGRGTIR
ESGSREYTAT RTTRQMADDY DDKEAYSQED EIDGAVFDRT TKLSTRHDFM PAEYGHGGVE
RRRNEMSTMT KSHETSYY
//
