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Database: UniProt
Entry: A0A0J9YUJ5_MOUSE
LinkDB: A0A0J9YUJ5_MOUSE
Original site: A0A0J9YUJ5_MOUSE 
ID   A0A0J9YUJ5_MOUSE        Unreviewed;       303 AA.
AC   A0A0J9YUJ5;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   30-AUG-2017, entry version 16.
DE   SubName: Full=Sodium channel protein type 1 subunit alpha {ECO:0000313|Ensembl:ENSMUSP00000144214};
DE   Flags: Fragment;
GN   Name=Scn1a {ECO:0000313|Ensembl:ENSMUSP00000144214,
GN   ECO:0000313|MGI:MGI:98246};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000144214, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000144214, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000144214,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA   She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA   Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA   Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA   Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA   Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of
RT   the mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000144214}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000144214};
RG   Ensembl;
RL   Submitted (AUG-2015) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000144214}.
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DR   EMBL; AL844526; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL928726; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSMUST00000200839; ENSMUSP00000144214; ENSMUSG00000064329.
DR   MGI; MGI:98246; Scn1a.
DR   GeneTree; ENSGT00830000128242; -.
DR   Proteomes; UP000000589; Chromosome 2.
DR   Bgee; ENSMUSG00000064329; -.
DR   ExpressionAtlas; A0A0J9YUJ5; baseline and differential.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR010526; Na_trans_assoc.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF06512; Na_trans_assoc; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    124    142       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    163    182       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    194    214       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        3    118       Na_trans_assoc. {ECO:0000259|Pfam:
FT                                PF06512}.
FT   DOMAIN      122    242       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSMUSP00000144214}.
SQ   SEQUENCE   303 AA;  34462 MW;  F4903D50DD300447 CRC64;
     XIDESDYMSF INNPSLTVTV PIAVGESDFE NLNTEDFSSE SDLEESKEKL NESSSSSEGS
     TVDIGAPAEE QPVIEPEETL EPEACFTEGC VQRFKCCQIS VEEGRGKQWW NLRRTCFRIV
     EHNWFETFIV FMILLSSGAL AFEDIYIDQR KTIKTMLEYA DKVFTYIFIL EMLLKWVAYG
     YQTYFTNAWC WLDFLIVDVS LVSLTANALG YSELGAIKSL RTLRALRPLR ALSRFEGMRD
     NLAPTWMGWS GGSSPQPFIM GGCECPVRSN SIHHECASGL PYILANFQHH GRKFVCWQIL
     PLC
//
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