ID A0A0K0DJP9_ANGCA Unreviewed; 341 AA.
AC A0A0K0DJP9;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 2.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Epimerase domain-containing protein {ECO:0000313|WBParaSite:ACAC_0001166101-mRNA-1};
OS Angiostrongylus cantonensis (Rat lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC Angiostrongylus.
OX NCBI_TaxID=6313 {ECO:0000313|Proteomes:UP000035642, ECO:0000313|WBParaSite:ACAC_0001166101-mRNA-1};
RN [1] {ECO:0000313|Proteomes:UP000035642}
RP NUCLEOTIDE SEQUENCE.
RA Martin A.A.;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:ACAC_0001166101-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
CC -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC {ECO:0000256|ARBA:ARBA00009219, ECO:0000256|RuleBase:RU004475}.
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DR AlphaFoldDB; A0A0K0DJP9; -.
DR STRING; 6313.A0A0K0DJP9; -.
DR WBParaSite; ACAC_0001166101-mRNA-1; ACAC_0001166101-mRNA-1; ACAC_0001166101.
DR Proteomes; UP000035642; Unassembled WGS sequence.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR PANTHER; PTHR43245:SF13; NAD(P)-BD_DOM DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01073; 3Beta_HSD; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU004475};
KW Reference proteome {ECO:0000313|Proteomes:UP000035642}.
FT DOMAIN 5..82
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
FT DOMAIN 153..269
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 341 AA; 38951 MW; E3EC0414ECBA3BFC CRC64;
MEVVAVTGAS GLVGRFVVDR LLKCGRYKEI RLIDRKPSAR TDADDVRVRP FVLDLVDEGA
LERALNGCNS VVHCAHAAMP WKYIDRKTND DIWRDNLSVH VGDAYSALPI EDNYGLGEYV
FKYRNSQHAG ERYLMLRKNM MNDYPGNYIL GEYGESHTRA EMYARNAVAR ARSGPSLQGV
FLRPVHVYAE QGSSSWITLM EMAQEGHVPY VKGDRRGLHQ FIYAGNLAAI VDRCLLLLAK
EPDRVNSEIV YCVDETSVIP FRDFLEQRVR SPRFSSQVAI SFEKAFLQQS LNYIKHTLGF
EVPKNALSFT MFRFLFAKTI GFSNRKQRLL LDFVPEVMKI F
//
