ID A0A0K0DUV3_STRER Unreviewed; 1193 AA.
AC A0A0K0DUV3;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};
OS Strongyloides stercoralis (Threadworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=6248 {ECO:0000313|WBParaSite:SSTP_0000102100.1};
RN [1] {ECO:0000313|WBParaSite:SSTP_0000102100.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (AUG-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR005719}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC3 subfamily.
CC {ECO:0000256|ARBA:ARBA00005917}.
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DR AlphaFoldDB; A0A0K0DUV3; -.
DR STRING; 6248.A0A0K0DUV3; -.
DR WBParaSite; SSTP_0000102100.1; SSTP_0000102100.1; SSTP_0000102100.
DR Proteomes; UP000035681; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR CDD; cd03272; ABC_SMC3_euk; 1.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR041741; SMC3_ABC_euk.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR PANTHER; PTHR43977; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR PANTHER; PTHR43977:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR005719};
KW Reference proteome {ECO:0000313|Proteomes:UP000035681}.
FT DOMAIN 534..647
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT REGION 235..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 407..448
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 672..783
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 810..913
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 979..1023
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 235..253
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1193 AA; 138892 MW; 60BF0A2F173B84C5 CRC64;
MYIKEICIHN FRSYKDKTVI NDLSKRHNVV VGRNGSGKSN FFFAIQFLLS DDFANLSQDA
RLNLLHEGAG EKVRSARVDI VFDNSDRRIM SYDINDLKIS REISERKDTF YIDGKIVSRS
EIVNLMESAG FSKSNPYYIV KQGKIMELAT STDAQRLALI KEVAGTRVYD EKKQDSAKLL
KENMDKLEKI EETIEFINER LKTLEEESND LREYQKYDKM KRALEYTIYE QEATDSRKKL
DNLSHEREEL NSQQNEIESS LLQYKQQSMK RETDLRRLEA TFKGVKEERE VLLEEQNVLV
EKKTNLELCI ADLREEADRE RKNRARAEEE MSSVGRIIND REIELEELEP SYKDVVEREN
NLLTDIKICE QKRKDLYIRQ GQQDQFRTTE DRDNYLRREC KKMDRYLSEL RERVAESEGL
IEQDRVETEE IQKNIMSLKL KLDRVMDRMD RLSGDQNQAK AHLEKCTIRQ GEIQREEKNW
HESMMNLNQE KSQVETDIRR MIPPSLMHGM NSIKKAIEHF KKNNKNGKYD YIINGYYGAL
VDLIDADDIF YHAIETTAGN SIYYSVVEDD RIASEITSYI NSSNLPGECN FCPLNRIVAK
PRKLITDPDA KHIMDCMKYD PKFETIIRSF FGQTAVVGSL DVGGRVSRTD NVNCVTLDGD
KISRRGPLTG GYREMKRSKL ELNNVLRQLN GNEIDMKKRS DEISKRANDA SISTAQAAQA
LENITEEIKR LRREHHLCNE ELSHKTEALN RMGMNIEPQR QHLQTHKNKI REIEAKKEIL
QNQIGTPLHS TLTDEEQAML ELLEKDMKER SIIESKKHKI ENELQNYLRR RREKLRCELQ
DISMEDKKHK LSSTNSELKS TNERLSNIME KINDIDTSLI DYKIQKDNLI KIKEEQQERI
KILENQLNDV GKRADVVCTK LATIRATNEE VTKKMAELGT LPQDAFKKFQ NLSRKKLDEK
LTECLVELKK YSNVNKRALD QFLRASQQKE DLVKRVQEQK KSKKAIENLI EVLDNRKNEA
LNMTFKMVTK HFHTVFQQLI PEGKADLILK LKDDDGPVPS GNELISVDRF VGVKIKCTFR
GDAESVEMNH LSGGQKTLIA LALIFAIQKC DPAPFYLFDE IDAALDAAHR SSVASMIHEL
SENAQFITTT FRPQLLEHAE KYYGVRFRNR VSHIDPVTKE QAYDFITDAE KRN
//
