ID   A0A0K0DYT7_STRER        Unreviewed;       608 AA.
AC   A0A0K0DYT7;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Xaa-Pro aminopeptidase 1 {ECO:0000313|WBParaSite:SSTP_0000240300.1};
OS   Strongyloides stercoralis (Threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=6248 {ECO:0000313|WBParaSite:SSTP_0000240300.1};
RN   [1] {ECO:0000313|WBParaSite:SSTP_0000240300.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (AUG-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase M24B family.
CC       {ECO:0000256|ARBA:ARBA00008766}.
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DR   AlphaFoldDB; A0A0K0DYT7; -.
DR   STRING; 6248.A0A0K0DYT7; -.
DR   WBParaSite; SSTP_0000240300.1; SSTP_0000240300.1; SSTP_0000240300.
DR   Proteomes; UP000035681; Unassembled WGS sequence.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR   CDD; cd01085; APP; 1.
DR   Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR   Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR   InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR   InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR   InterPro; IPR000587; Creatinase_N.
DR   InterPro; IPR000994; Pept_M24.
DR   InterPro; IPR033740; Pept_M24B.
DR   InterPro; IPR032416; Peptidase_M24_C.
DR   PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR   PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR   Pfam; PF01321; Creatinase_N; 1.
DR   Pfam; PF16189; Creatinase_N_2; 1.
DR   Pfam; PF00557; Peptidase_M24; 1.
DR   Pfam; PF16188; Peptidase_M24_C; 1.
DR   SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR   SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000035681}.
FT   DOMAIN          42..141
FT                   /note="Creatinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01321"
FT   DOMAIN          317..533
FT                   /note="Peptidase M24"
FT                   /evidence="ECO:0000259|Pfam:PF00557"
FT   DOMAIN          544..608
FT                   /note="Peptidase M24 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16188"
SQ   SEQUENCE   608 AA;  69648 MW;  17062FB726044AEA CRC64;
     MSKKLQLLRN LMKNGSLTNG KIVNAYLLPR TDPHESEYIS NHYQRVKFIS GFSGSNAMVL
     VTDSKALCWT DGRYFDQAIQ EFEEGWELMK QAVPDSITPT EWLSLNIPNG SVIGFDPHLV
     SQETVKTMKN KLEVMKMELL PIEKNFIDEL WESRPKEDIK GVRLLGIEYT GEDVFSKIER
     LRKILKDKKC DSIILTLLDD IAWLYNIRGN DIDYNPVVFS YAFVTMDEAY LFINKKKLPE
     GYEEHLKGIQ IFDYEKVSDV LKEYHNNKSK DNIFYKMWIP STTNYGLSSL ISETNIYDSL
     SPVQILKATK NETELKGMRE AHIRDSSAVI EFLIWLEEEL KSGKVLSEKI AMNKLDTLRS
     TKDKFVSLSF DTISAVNEHA ALPHYKMTEK SSLPLKFGDV YLVDSGGQYL DGTTDVTRTV
     IVGNNINNEF IDLFTQVLIG HIECAMAKFP EGILGCRLDS FARHCLWENG YDFGHGTGHS
     FGSFLNVHEG PGSIGFRNSN ENGKLKAGQM MTIEPGYYRT LNWGIRIENC YEIIKCNVNS
     GASNFLTFSP LTLVPIQKKL INKNMLSIKQ VNWLNDYHRV VYDTMTNYFT RYSQEKEILW
     LKEACAPI
//