ID A0A0K0E8F7_STRER Unreviewed; 809 AA.
AC A0A0K0E8F7;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Lipase_3 domain-containing protein {ECO:0000313|WBParaSite:SSTP_0000578800.1};
OS Strongyloides stercoralis (Threadworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=6248 {ECO:0000313|WBParaSite:SSTP_0000578800.1};
RN [1] {ECO:0000313|WBParaSite:SSTP_0000578800.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (AUG-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the otopetrin family.
CC {ECO:0000256|ARBA:ARBA00006513}.
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DR AlphaFoldDB; A0A0K0E8F7; -.
DR WBParaSite; SSTP_0000578800.1; SSTP_0000578800.1; SSTP_0000578800.
DR Proteomes; UP000035681; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015252; F:proton channel activity; IEA:InterPro.
DR InterPro; IPR004878; Otopetrin.
DR PANTHER; PTHR21522:SF43; OTOPETRIN-LIKE; 1.
DR PANTHER; PTHR21522; PROTON CHANNEL OTOP; 1.
DR Pfam; PF03189; Otopetrin; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000035681};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 116..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 217..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 561..583
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 595..616
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 683..708
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 729..746
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 809 AA; 91914 MW; 53923EB132B2C832 CRC64;
MENISDSKNE AFNNEENTVV EPITESPIIT SKWNLNTSEE YVSSLSLTSP QTVSSTAYLF
DDQDDIELSK NSILYHNKNL RKKNYNSSDT ISLNSKLYNN HKINITNIEN KNSKAAFSHL
ISCITILYAI LAIVYSIVQE TVQQANNATW QAEMILYTLM YGFGIIFLVY CYLFIIYPTW
YNKLLQIFLR KNIISERTYH NHTLAPTSHH GEGAGSLYLR LGVLFFGSAG IVLFFLEIML
CFTCENCLPH SMINLILSGL FTFLQMHFIF CNSKIVVSKQ RSIAKFGTMH LLAVNIWTWF
RMVLAKKNKG KIKKILLENN PTVNITNNVQ STLKNLVENF SPSSFDIVAG SSIDAIDDVI
NNSSMNASSY IIKSKNVFDK FNLTQDTMKN ILTSTVETFL DNSTDVGYHH EVISIPSSIS
SSLKFRSYPN KTVLGKITAY EYFGDFTTFV ITCIVEYSVI GAAIMFVMWK VLSEEDDLIN
DKQNDSLSVC QSQNLFQQND NKSNDSINSE CLCERNSSFA NCESNSKQSS ISIIRERMSQ
KSIVKAKRKN RVSIDCSASS SGLFCGILFL ICCFVSVLMY CVFYQQQKND SAIHVFRVAD
LIMFTVMIFA VIIGLFQMTK LNYEDDLLLG VGLVGEQIHS CIGIIVWIGV LYSKEDKFQS
NTKENLENTI NIFLPLQNLP SNLYINILSI LVFITRIIES TLQALFILIA SRMKATSKYA
KLKKPGKQFV TFLLIANVSL FFFHTLEGMK CIFGNTESYS TKEVNETRIK IENYLSLVYS
VSPLVIFFRF HSSVCLAEIW KHCYSEKTH
//
