ID   A0A0K0EA13_STRER        Unreviewed;       534 AA.
AC   A0A0K0EA13;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=RhoGAP domain containing protein {ECO:0000313|WBParaSite:SSTP_0000634500.1};
OS   Strongyloides stercoralis (Threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=6248 {ECO:0000313|WBParaSite:SSTP_0000634500.1};
RN   [1] {ECO:0000313|WBParaSite:SSTP_0000634500.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (AUG-2015) to UniProtKB.
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DR   AlphaFoldDB; A0A0K0EA13; -.
DR   STRING; 6248.A0A0K0EA13; -.
DR   WBParaSite; SSTP_0000634500.1; SSTP_0000634500.1; SSTP_0000634500.
DR   Proteomes; UP000035681; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd00029; C1; 1.
DR   Gene3D; 3.30.60.20; -; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR046349; C1-like_sf.
DR   InterPro; IPR002219; PE/DAG-bd.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR46199:SF3; FI24033P1-RELATED; 1.
DR   PANTHER; PTHR46199; RAC GTPASE-ACTIVATING PROTEIN 1; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
DR   PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR   PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035681};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          240..288
FT                   /note="Phorbol-ester/DAG-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50081"
FT   DOMAIN          303..494
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          127..151
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          63..111
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   534 AA;  60758 MW;  A36921480C3B99A6 CRC64;
     MDRKSQSIDS LSLLEEHVQL VSAYESLFAS SSQDIIDAYE FTLSECEEAS SFKKELNEII
     NFCDNVVEKN KVLEEKLKKY KEEITLLKEN ISKYEKENKH LKNCVENLKN VFSVKIEKVK
     TKMKDSNMVS TDSEDDIDFD MTGESGVSEE GKITLKQQTP KISNEEEDFS SRKSLASDTV
     IDNLRRSASD VPKRQHKIER RDFNLTVAVE NPLAIEPIKE YIESTSNLSW TNGSYISEKT
     HRFYTKGFHI GICNICDSIL FKSKNVLSCS DCQLLGHTNC LFNTTIPCVP RNSFPKIVNR
     MRLSLAECCP ESNPMIPYII IRCVIAIEQF YIKNEGIYRV PGNPENIQRL FISLKNPKTT
     ADLSKEFPET IVGCIKRFLR ELREPLIPSS SWDEFTSAAE IKDINGINLA FCDLPRPNAD
     TLAFICAHLQ KVIENSDINK MPIENISQIM GPIIVGFPKK SRSSDGISPT TKEHDVEKQI
     TTMKTLLSLP PTYWDPFLKP KSTRNRRSSL SRPISTLNTL NHSVRYSLGA NPDF
//