ID   A0A0K0EL78_STRER        Unreviewed;       349 AA.
AC   A0A0K0EL78;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Sidoreflexin {ECO:0000256|RuleBase:RU362000};
OS   Strongyloides stercoralis (Threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=6248 {ECO:0000313|WBParaSite:SSTP_0001022200.1};
RN   [1] {ECO:0000313|WBParaSite:SSTP_0001022200.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (AUG-2015) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC       membrane {ECO:0000256|RuleBase:RU362000}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU362000}.
CC   -!- SIMILARITY: Belongs to the sideroflexin family.
CC       {ECO:0000256|ARBA:ARBA00005974, ECO:0000256|RuleBase:RU362000}.
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DR   AlphaFoldDB; A0A0K0EL78; -.
DR   STRING; 6248.A0A0K0EL78; -.
DR   WBParaSite; SSTP_0001022200.1; SSTP_0001022200.1; SSTP_0001022200.
DR   Proteomes; UP000035681; Unassembled WGS sequence.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015075; F:monoatomic ion transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR004686; Mtc.
DR   NCBIfam; TIGR00798; mtc; 1.
DR   PANTHER; PTHR11153; SIDEROFLEXIN; 1.
DR   PANTHER; PTHR11153:SF6; SIDEROFLEXIN-5; 1.
DR   Pfam; PF03820; SFXNs; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362000};
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128,
KW   ECO:0000256|RuleBase:RU362000};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035681};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362000};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362000}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        176..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362000"
FT   TRANSMEM        207..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362000"
FT   TRANSMEM        267..285
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362000"
FT   TRANSMEM        297..319
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362000"
SQ   SEQUENCE   349 AA;  39580 MW;  E0D4A3D217F2A59F CRC64;
     MEKKSFIRQR KVLVIFFLIE IMSSETIFGF PKYPKFDISS QRFPQDTFFG RYLHYLDVID
     PRTLLVSDEK LKKCTKLLND YKSGLVKNVS DKELWEAKKV CNAILHPDTG EKIFSPFRMA
     GFVPYGWITV TGMLLPNPTW PQIIFWQWMN QSHNAAVNYA NRNSTNPQPT SVYVKAYTVA
     VSTAVGISTA LTYAIKKSNN LDPIKKLIIQ RFVPLPACSL ASTFNILAMR LPEIESGIDV
     YDKNGNVIGT SKIAAKRAVF ETASTRAFLP IPLLLAPPCI MPFIEKYKFM KNKRISLFVN
     AIVCTLSFAA SLPVALALFP QESKINTIDL EDEIRKKTTS KILYYNKGM
//