ID A0A0K0J4M6_BRUMA Unreviewed; 183 AA.
AC A0A0K0J4M6; A0A0H5SHL7;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 3.
DT 13-SEP-2023, entry version 39.
DE SubName: Full=Bm2149 {ECO:0000313|EMBL:CRZ23344.1};
DE SubName: Full=PUA domain-containing protein {ECO:0000313|WBParaSite:Bm2149.1};
GN Name=Bm1_36830 {ECO:0000313|WBParaSite:Bm2149.1};
GN ORFNames=Bm2149 {ECO:0000313|EMBL:CRZ23344.1,
GN ECO:0000313|WormBase:Bm2149}, BM_Bm2149 {ECO:0000313|EMBL:CRZ23344.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CRZ23344.1};
RN [1] {ECO:0000313|EMBL:CRZ23344.1, ECO:0000313|Proteomes:UP000006672}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ23344.1,
RC ECO:0000313|Proteomes:UP000006672};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CRZ23344.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ23344.1};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:Bm2149.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2022) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|PIRNR:PIRNR005067}.
CC -!- SIMILARITY: Belongs to the MCTS1 family.
CC {ECO:0000256|ARBA:ARBA00008955}.
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DR EMBL; LN856865; CRZ23344.1; -; Genomic_DNA.
DR RefSeq; XP_001898813.1; XM_001898778.1.
DR AlphaFoldDB; A0A0K0J4M6; -.
DR EnsemblMetazoa; Bm2149.1; Bm2149.1; WBGene00222410.
DR GeneID; 6102251; -.
DR KEGG; bmy:BM_BM2149; -.
DR WBParaSite; Bm2149.1; Bm2149.1; WBGene00222410.
DR CTD; 6102251; -.
DR WormBase; Bm2149; BM22616; WBGene00222410; -.
DR OMA; SINKGHG; -.
DR OrthoDB; 5036262at2759; -.
DR Proteomes; UP000006672; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR CDD; cd11609; MCT1_N; 1.
DR CDD; cd21155; PUA_MCTS-1-like; 1.
DR Gene3D; 3.10.400.20; -; 1.
DR InterPro; IPR016437; MCT-1/Tma20.
DR InterPro; IPR041366; Pre-PUA.
DR InterPro; IPR002478; PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR004521; Uncharacterised_CHP00451.
DR NCBIfam; TIGR00451; unchar_dom_2; 1.
DR PANTHER; PTHR22798:SF0; MALIGNANT T-CELL-AMPLIFIED SEQUENCE 1; 1.
DR PANTHER; PTHR22798; MCT-1 PROTEIN; 1.
DR Pfam; PF17832; Pre-PUA; 1.
DR Pfam; PF01472; PUA; 1.
DR PIRSF; PIRSF005067; Tma_RNA-bind_prd; 1.
DR SMART; SM00359; PUA; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR PROSITE; PS50890; PUA; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR005067};
KW Reference proteome {ECO:0000313|Proteomes:UP000006672}.
FT DOMAIN 94..173
FT /note="PUA"
FT /evidence="ECO:0000259|SMART:SM00359"
SQ SEQUENCE 183 AA; 20553 MW; 469CEFA7C39E1A80 CRC64;
MFKKFDEKED IIGTQQLKSS AQKSIRSKIV DQLPLLDDYI NDILPKKDSF KLIKCKEHVE
LIADCEGKIL FIKPRDVPYF PTLRLLHQYP FILPHEKVDK GAIKFVLNGS QIMCRGLTSP
GARLNVDVPE NSVVALMAEG KKHALAIGLT KMSADEILTV NKGIGIENLH HLNDGLWKVP
TVL
//
