ID A0A0K0J9L8_BRUMA Unreviewed; 226 AA.
AC A0A0K0J9L8;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=BMA-ERCC-1, isoform b {ECO:0000313|EMBL:CDP97272.1};
DE SubName: Full=Helix-hairpin-helix motif family protein {ECO:0000313|WBParaSite:Bm3288a.1};
GN Name=bma-ercc-1 {ECO:0000313|WormBase:Bm3288b};
GN Synonyms=Bma-ercc-1 {ECO:0000313|EMBL:CDP97272.1};
GN ORFNames=Bm3288 {ECO:0000313|WormBase:Bm3288b}, BM_Bm3288
GN {ECO:0000313|EMBL:CDP97272.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CDP97272.1};
RN [1] {ECO:0000313|EMBL:CDP97272.1, ECO:0000313|Proteomes:UP000006672}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP97272.1,
RC ECO:0000313|Proteomes:UP000006672};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CDP97272.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP97272.1};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:Bm3288a.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2022) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ERCC1/RAD10/SWI10 family.
CC {ECO:0000256|ARBA:ARBA00008283}.
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DR EMBL; LN856980; CDP97272.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0K0J9L8; -.
DR EnsemblMetazoa; Bm3288a.1; Bm3288a.1; WBGene00223549.
DR WBParaSite; Bm3288a.1; Bm3288a.1; WBGene00223549.
DR WormBase; Bm3288b; BM37567; WBGene00223549; Bma-ercc-1.
DR OMA; RPPDLIM; -.
DR OrthoDB; 12065at2759; -.
DR Proteomes; UP000006672; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProt.
DR GO; GO:0006302; P:double-strand break repair; IEA:UniProt.
DR CDD; cd22325; ERCC1_C-like; 1.
DR Gene3D; 3.40.50.10130; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR InterPro; IPR047260; ERCC1-like_central_dom.
DR InterPro; IPR004579; ERCC1/RAD10/SWI10.
DR InterPro; IPR011335; Restrct_endonuc-II-like.
DR InterPro; IPR010994; RuvA_2-like.
DR NCBIfam; TIGR00597; rad10; 1.
DR PANTHER; PTHR12749:SF0; DNA EXCISION REPAIR PROTEIN ERCC-1; 1.
DR PANTHER; PTHR12749; EXCISION REPAIR CROSS-COMPLEMENTING 1 ERCC1; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF03834; Rad10; 1.
DR SUPFAM; SSF52980; Restriction endonuclease-like; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000006672}.
FT DOMAIN 20..130
FT /note="ERCC1-like central"
FT /evidence="ECO:0000259|Pfam:PF03834"
SQ SEQUENCE 226 AA; 25890 MW; F73BFDBBCDA1589B CRC64;
MEMEIPSSSQ SGALLNSRLI INRKRQEGNP VLKYIRNVPF EWAEIKADFE AGKEMGILYL
SLKWHKLHPN YIETRINSDG AGYAIKILLV LVNVEPRHIL RELNLFCYRT GWTLMLCYSA
EEAAEYLENL HISRNRNEQS AINAMQERKK KRLCLPDEDN EFHQAVKFLT VIRSLTVSDA
QRLIATFGSI RKIANADIDR LLLCPGLGPT KAGNIHAFFR SSFQKA
//
