ID A0A0K0JM48_BRUMA Unreviewed; 520 AA.
AC A0A0K0JM48;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=N-acetyl-D-glucosamine kinase {ECO:0000256|ARBA:ARBA00014974};
DE EC=2.7.1.59 {ECO:0000256|ARBA:ARBA00012122};
DE AltName: Full=GlcNAc kinase {ECO:0000256|ARBA:ARBA00031123};
GN ORFNames=Bm6204 {ECO:0000313|EMBL:CTP81402.1,
GN ECO:0000313|WBParaSite:Bm6204.1, ECO:0000313|WormBase:Bm6204},
GN BM_Bm6204 {ECO:0000313|EMBL:CTP81402.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|Proteomes:UP000006672, ECO:0000313|WBParaSite:Bm6204.1};
RN [1] {ECO:0000313|EMBL:CTP81402.1, ECO:0000313|Proteomes:UP000006672}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CTP81402.1,
RC ECO:0000313|Proteomes:UP000006672};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CTP81402.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CTP81402.1};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:Bm6204.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2019) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eukaryotic-type N-acetylglucosamine kinase
CC family. {ECO:0000256|ARBA:ARBA00006198}.
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DR EMBL; LN856981; CTP81402.1; -; Genomic_DNA.
DR STRING; 6279.A0A0K0JM48; -.
DR EnsemblMetazoa; Bm6204.1; Bm6204.1; WBGene00226465.
DR WBParaSite; Bm6204.1; Bm6204.1; WBGene00226465.
DR WormBase; Bm6204; BM22610; WBGene00226465; -.
DR OMA; VGGWGHQ; -.
DR OrthoDB; 3030525at2759; -.
DR Proteomes; UP000006672; Unassembled WGS sequence.
DR GO; GO:0045127; F:N-acetylglucosamine kinase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002731; ATPase_BadF.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR019410; Methyltransf_16.
DR InterPro; IPR039758; NAGK_prok_euk.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12862; BADF TYPE ATPASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12862:SF0; N-ACETYL-D-GLUCOSAMINE KINASE; 1.
DR Pfam; PF01869; BcrAD_BadFG; 1.
DR Pfam; PF10294; Methyltransf_16; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006672}.
FT DOMAIN 197..498
FT /note="ATPase BadF/BadG/BcrA/BcrD type"
FT /evidence="ECO:0000259|Pfam:PF01869"
SQ SEQUENCE 520 AA; 57308 MW; 81790D26B35B6751 CRC64;
MMAEHWRHVW QSSEVLGDYI SAHHYLFEGC TVLELGAGCT GIPGLVAAKC GAKLVIFTDH
PESEEAFKIL KQNCVVNNLD ENCFLIKDLD WNGSDLNQVM DDVLVLHYIL AADVFYDITV
FEPFVHTVAL LLQLYPKATC IFAYEERNSN WSIEDLLLLN KLCCRRVRVV HTDLHTIHIG
IIFNKTDFME ASRIFAGIEG GATQSRLLFI DEAGKRYGEW SRTGLNCCLD GFDVVADRIA
KWIQMAKKEV GIVGPLAAVG MGLSGAEDEK SNQRLINFLK DQHGDIAVEF SLSSDAVVAA
AASFQNGGAV IVAGTGSACR LLKADSSVYG VGGWGHQIGD GGSAFWIARR LIQCIFDEED
GLHPSPHSIS KTKRLFLEFF DLSDKAGILD ILYTNFDKSR IASFAAHVAK EANDDPLVRL
VFRDAGEQLG LHVRAISRNF DEEMLHNAPL LLIGSVWRSW ELLKDGFVHG LKSNGSRIGK
VTLYTLLETP ALGAALLAAR KIGKKVACEQ RTAILEVLIL
//
