GenomeNet

Database: UniProt
Entry: A0A0K0U136_9RHIZ
LinkDB: A0A0K0U136_9RHIZ
Original site: A0A0K0U136_9RHIZ 
ID   A0A0K0U136_9RHIZ        Unreviewed;       491 AA.
AC   A0A0K0U136;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   05-JUL-2017, entry version 15.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=DnaA {ECO:0000313|EMBL:AKR57710.1};
GN   Synonyms=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=XM25_18360 {ECO:0000313|EMBL:AKR57710.1};
OS   Devosia sp. H5989.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Hyphomicrobiaceae; Devosia.
OX   NCBI_TaxID=1643450 {ECO:0000313|EMBL:AKR57710.1, ECO:0000313|Proteomes:UP000037066};
RN   [1] {ECO:0000313|EMBL:AKR57710.1, ECO:0000313|Proteomes:UP000037066}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H5989 {ECO:0000313|EMBL:AKR57710.1,
RC   ECO:0000313|Proteomes:UP000037066};
RX   PubMed=26337876;
RA   Nicholson A.C., Whitney A.M., Humrighouse B., Emery B., Loparev V.,
RA   McQuiston J.R.;
RT   "Complete Genome Sequence of Strain H5989 of a Novel Devosia
RT   Species.";
RL   Genome 3:e00934-15(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP011300; AKR57710.1; -; Genomic_DNA.
DR   RefSeq; WP_049707141.1; NZ_CP011300.1.
DR   EnsemblBacteria; AKR57710; AKR57710; XM25_18360.
DR   KEGG; deq:XM25_18360; -.
DR   PATRIC; fig|1643450.3.peg.3716; -.
DR   KO; K02313; -.
DR   Proteomes; UP000037066; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000037066};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037066}.
FT   DOMAIN      184    404       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      399    468       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     192    199       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   491 AA;  54093 MW;  3260C59EEF3E2267 CRC64;
     MAEDQAGNST EQRELFARVR ARLRAAVGED VFTSWFARLE LEELVDDLAH LSVPTRFLCS
     WIQSNYAERI LEAFQGESQA IGRLHFTVRV NGQARPRLAP VVEASAPEQS ASAAAPKPIE
     VVQPAAPRLI RDTPAAAAAK ADALSGSALD PRQTFETFVP GSANEIALGV AKQVAHAVVN
     NTVSFNPVYI HSTVGLGKSH LLNAIAWAAG ANEPGRNIVY LTADHFMYHF ITAVQRQSAL
     GFKEWLRRVD LLLIDDMQFL QGKSATEFGH TLGALLTGAK QVVVAGDAAP RDLEMLDERV
     RSRLSGGLVV PIMTFDGDLR RSIVMKRAEQ AAARFAGVTF PPAVIDYVAR VVVSHGRDLD
     GAVNRLVAAN QLTGEPITVA LAEKTLADLI RAREARRVRI EDILRIVSRH YKVPRNDLLS
     SRRSRDVVRP RQIAMYLAKS LTSRSLPEIG RRFGGRDHTT VLHSVRKVEQ MMKDDGDLCQ
     EIELLKRMLE E
//
DBGET integrated database retrieval system