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Database: UniProt
Entry: A0A0K1F8K5_9MICO
LinkDB: A0A0K1F8K5_9MICO
Original site: A0A0K1F8K5_9MICO 
ID   A0A0K1F8K5_9MICO        Unreviewed;       573 AA.
AC   A0A0K1F8K5;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   25-OCT-2017, entry version 19.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=ADJ73_05230 {ECO:0000313|EMBL:AKT50853.1};
OS   Arsenicicoccus sp. oral taxon 190.
OC   Bacteria; Actinobacteria; Micrococcales; Intrasporangiaceae;
OC   Arsenicicoccus.
OX   NCBI_TaxID=1658671 {ECO:0000313|EMBL:AKT50853.1, ECO:0000313|Proteomes:UP000065578};
RN   [1] {ECO:0000313|EMBL:AKT50853.1, ECO:0000313|Proteomes:UP000065578}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0371 {ECO:0000313|EMBL:AKT50853.1,
RC   ECO:0000313|Proteomes:UP000065578};
RA   Noorani M.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP012070; AKT50853.1; -; Genomic_DNA.
DR   EnsemblBacteria; AKT50853; AKT50853; ADJ73_05230.
DR   KEGG; ars:ADJ73_05230; -.
DR   PATRIC; fig|1658671.3.peg.1061; -.
DR   KO; K02313; -.
DR   Proteomes; UP000065578; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000065578};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000065578}.
FT   DOMAIN      266    396       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      478    547       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     274    281       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   573 AA;  63950 MW;  209A96DFBC9E1F49 CRC64;
     MTEAQVDVPR VWRDTLRTLE ARGISAQHRG FLRLSRLVGL LEGTALIAVP NDYTRDIVEK
     RIRAELVLAL QEQLGRDVRL AVTVDSSLEL SEAEDRDDDL HRGAGDEHPT VLTSDDRSRE
     QVEAPLQHDA GPGHPGHPGH HSDGLRATDP VRATDSLRLV RDERIHRVGP AGPGHGHDEQ
     HRPEGGDHGW QSGIRAVPAA DDDDEDRELL AEGAGIREMF RKPFVPEDGG DAQLNPKYTF
     DTFVIGSSNR FAHAAAIAVA EAPAKAYNPL FIYGGSGLGK THLLHAIGHY AQQIYPNVRV
     KYVNSEEFTN DFINSIGANK ASDFQRRYRD VDFLLIDDIQ FLQGKVQTQE EFFHTFNTLH
     NANKQVVITS DVAPKLLSGF EERMRSRFEW GLLTDVQPPD LETRIAILRK KAVQERMTSP
     DDVLEFIASR ISTNIRELEG ALIRVTAFAS LNHQAVDMTL AEIVLKDLIP ADQTNQITPA
     TIMAQTASYF GLTVDDLCGT SRSRVLVTAR QIAMYLCREL TDLSLPKIGQ QFGGRDHTTV
     MHADRKIREL MSERRAIYNQ VTELTNRIKS NPA
//
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