GenomeNet

Database: UniProt
Entry: A0A0K1IZK6_9RHOO
LinkDB: A0A0K1IZK6_9RHOO
Original site: A0A0K1IZK6_9RHOO 
ID   A0A0K1IZK6_9RHOO        Unreviewed;       475 AA.
AC   A0A0K1IZK6;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-SEP-2017, entry version 17.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AzCIB_0001 {ECO:0000313|EMBL:AKU09906.1};
OS   Azoarcus sp. CIB.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Rhodocyclales;
OC   Zoogloeaceae; Azoarcus.
OX   NCBI_TaxID=198107 {ECO:0000313|EMBL:AKU09906.1, ECO:0000313|Proteomes:UP000066621};
RN   [1] {ECO:0000313|EMBL:AKU09906.1, ECO:0000313|Proteomes:UP000066621}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIB {ECO:0000313|EMBL:AKU09906.1,
RC   ECO:0000313|Proteomes:UP000066621};
RA   Martin-Moldes Z., Zamarro M.T., del Cerro C., Valencia A., Gomez M.J.,
RA   Udaondo Z., Garcia J.L., Nogales J., Carmona M., Diaz E.;
RT   "Whole-genome analysis of Azoarcus sp. strain CIB provides genetic
RT   insights to its different lifestyles and predicts novel metabolic
RT   features.";
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP011072; AKU09906.1; -; Genomic_DNA.
DR   RefSeq; WP_050418126.1; NZ_CP011072.1.
DR   EnsemblBacteria; AKU09906; AKU09906; AzCIB_0001.
DR   KEGG; azi:AzCIB_0001; -.
DR   PATRIC; fig|198107.6.peg.1; -.
DR   KO; K02313; -.
DR   Proteomes; UP000066621; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000066621};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000066621}.
FT   DOMAIN      172    303       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      383    452       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     180    187       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   475 AA;  53534 MW;  1ABDDDD38F0D372D CRC64;
     MSQDFWSFCL SRLESELPPQ QFNTWIKTLR AEAGTSEEPS LRLFAPNRFV MQWVRERYLK
     RIAELGEEFH GGPLLLELVM AEAGSARTAA RPVAPVMPVA SEGAAANATP APIAAPAIIT
     RPEPEPAITS ADLAYEKTRL NPDFTFDTLV TGRANDLARA AAMQVAQNPG TSYNPLFVYG
     GVGLGKTHLV HAIGNAVYRR NPRAVIRYVH VEDYYADVVR AYQQKSFDAF KRYYRSLDLL
     LIDDIQFFNN KNRTQEEFFH AFNALTEARK QIVITCDTYP KDIQGLEDRL ISRFDWGLTV
     QIEPPELEMR VAILQKKAEA LRVDLHDDVA FLIAKNLRSN VRELEGALNK VVAFARFHGR
     GISLEVAKDA LKDLLNAHNR QLTIEHIQKT VADYYKIKVA DMHSKKRTRV IARPRQVAMW
     LAKDLTPMSL PAIGEAFGGR DHTTVLHACR TIADLRLGDQ QLNHDVHVLT QVLRG
//
DBGET integrated database retrieval system