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Database: UniProt
Entry: A0A0K1JEG8_9MICO
LinkDB: A0A0K1JEG8_9MICO
Original site: A0A0K1JEG8_9MICO 
ID   A0A0K1JEG8_9MICO        Unreviewed;       488 AA.
AC   A0A0K1JEG8;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   25-OCT-2017, entry version 18.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=VV02_02415 {ECO:0000313|EMBL:AKU14985.1};
OS   Luteipulveratus mongoliensis.
OC   Bacteria; Actinobacteria; Micrococcales; Dermacoccaceae;
OC   Luteipulveratus.
OX   NCBI_TaxID=571913 {ECO:0000313|EMBL:AKU14985.1, ECO:0000313|Proteomes:UP000066480};
RN   [1] {ECO:0000313|EMBL:AKU14985.1, ECO:0000313|Proteomes:UP000066480}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MN07-A0370 {ECO:0000313|EMBL:AKU14985.1,
RC   ECO:0000313|Proteomes:UP000066480};
RA   Juboi H., Basik A., Shamsul S.S., Arnold P., Schmitt E.K.,
RA   Sanglier J.-J., Yeo T.;
RT   "Luteipulveratus halotolerans sp. nov., a novel actinobacterium
RT   (Dermacoccaceae) from Sarawak, Malaysia.";
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP011112; AKU14985.1; -; Genomic_DNA.
DR   RefSeq; WP_052589551.1; NZ_CP011112.1.
DR   EnsemblBacteria; AKU14985; AKU14985; VV02_02415.
DR   KEGG; lmoi:VV02_02415; -.
DR   PATRIC; fig|571913.6.peg.496; -.
DR   KO; K02313; -.
DR   Proteomes; UP000066480; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000066480};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000066480}.
FT   DOMAIN      179    311       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      392    461       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     187    194       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   488 AA;  54516 MW;  B1248829674C26ED CRC64;
     MTVSEHQPDL AHVWHSTVLA LEETGIAARD RAFLRLTRLV GLVDQTALLA VPFDHTKDIL
     ETTLREPVSA ALSRHLNRDV RLAITVDPQL RQTVDGSAEA REAGIGEDEV AETEAEERAT
     RDTVVPLRAS VPMTTTRPVE PVTDARLNPK YTFDTFVIGA SNRFAHAAAF AVAEAPAKSY
     NPLFVYGDSG LGKTHLLHAI GHYVRNLYPS MRVRYVNSEE FTNDFINSIR DDKASSFQKR
     YRDDVDVLLI DDVQFLQGKD GTQEEFFHTF NALHDGEKQI VLTSDQPPKK LSGFADRMRS
     RFEWGLQTDV TPPDLETRIA ILRKKAIAER MNVPDDVLEL IASKFSTNIR ELEGALIRVM
     AFASLSQQPV DQQVAGYVLK DLVPSASTGQ ITATLIMTKT AEYFHVSVEE LCGSSRSRTL
     VTARQIAMYL CRELTELSLP KIGQQFGGRD HTTVMHADRK IRQLIGERRP IYDQITELTS
     QITRAAAG
//
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