ID A0A0K2RMB0_9MICC Unreviewed; 259 AA.
AC A0A0K2RMB0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN ORFNames=AHiyo8_42830 {ECO:0000313|EMBL:BAS15980.1};
OS Arthrobacter sp. Hiyo8.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=1588023 {ECO:0000313|EMBL:BAS15980.1, ECO:0000313|Proteomes:UP000060353};
RN [1] {ECO:0000313|Proteomes:UP000060353}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hiyo8 {ECO:0000313|Proteomes:UP000060353};
RA Hiraoka S., Machiyama A., Iwasaki W.;
RT "Microbial genome analysis of tsunami-affected soil.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
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DR EMBL; AP014719; BAS15980.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0K2RMB0; -.
DR STRING; 1588023.AHiyo8_42830; -.
DR KEGG; arh:AHiyo8_42830; -.
DR PATRIC; fig|1588023.3.peg.4468; -.
DR Proteomes; UP000060353; Chromosome.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 25..210
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
FT REGION 227..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 259 AA; 27666 MW; DDB14A6F3C458CE7 CRC64;
MKKILMVLTS VSELGDTGKK TGYNVAEAAH PWKVFKDSGH FVDFASIQGG QPPRDEVDSK
DPIQVAFTED EATRAGLYNT ARVDVVDPGQ YDAVFLVGGH GTMWDFPDSE GLQKLVASVY
DAGGVVGAVC HGPAGLVNVD LADGFRLVGG REVAAFTNDE EVAAGMDKVI PFFLADRLKE
QGAIHVFADV FAEKVVVSDR LVTGQNHASA AGVAKEMEKL LAEVIHQEKA EEQQESEALR
AEKDAKKEAK KAAAAGTEH
//
