ID A0A0K2YJH8_9NOCA Unreviewed; 741 AA.
AC A0A0K2YJH8;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=RHCRD62_20294 {ECO:0000313|EMBL:CRK50855.1};
OS Rhodococcus sp. RD6.2.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=260936 {ECO:0000313|EMBL:CRK50855.1, ECO:0000313|Proteomes:UP000044872};
RN [1] {ECO:0000313|EMBL:CRK50855.1, ECO:0000313|Proteomes:UP000044872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RD6.2 {ECO:0000313|EMBL:CRK50855.1,
RC ECO:0000313|Proteomes:UP000044872};
RA Wang D.B., Wang M.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
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DR EMBL; CVQP01000005; CRK50855.1; -; Genomic_DNA.
DR RefSeq; WP_050064145.1; NZ_CVQP01000005.1.
DR AlphaFoldDB; A0A0K2YJH8; -.
DR STRING; 260936.RHCRD62_20294; -.
DR OrthoDB; 2365435at2; -.
DR Proteomes; UP000044872; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000044872};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 22..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 569..586
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 593..614
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 626..646
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 667..695
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 219..349
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 596..724
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 741 AA; 77000 MW; 5E45259C21B04C1D CRC64;
MTDVDLDTEP ARYPPPAPRR GWPVLAVLVL AVLVFLVGGA GGAYQGKLTE VQKNDNAAFL
PESAESTIAA NEAATFVTVQ TIPGFVVYHR DGPLTPEDRA SIARAGEAVA GVDGVDATGM
TPTQYSADGT TAAQYVPLVA KKDGTDVTGD QLAATEQQVM DAAKAAATAE LEVLPAGPGG
LLVAFIDAFE GLDSTLLFAA VLVVIAILLV VYRSPVLWFF PLLSAGLALG LSSMLIYLLA
KAEVLTLTGQ SQGILMVLVL GAGTDYALLL ISRYREELHH FPNRFDAMIR AWRESAPAIT
ASALTVVLGL LCLGFSELNS NKGLGPVAAI GIGCTYLVMM TFLPVFLALA GRWVFWPRIP
HVDHAADLAT HGWWGRIAAA VGRRDRPAWV GATALLVVLF AVGIGSLHTS GLTSAENFTN
TPDAVTGQQI YDTHFDPGTG APAVIVTNAD QVDAVMAAAA ATPGVSTAPG SVCLQVDYAK
LAELAKLGAG TGSALPAGCP PPILTVQPID GRTVVNATLA DSYDSPEALA TVDRLRDAVH
AVPGADALVG GSTAATADVQ AASVRDRNVI IPIVLAVIFV VLALLLRALL APVILIATVV
LSFAATLGVC GFVFTHVFHF AGADPSFPLF AFVFLVALGI DYNIFLMTRV REEAQRHGTR
AGVLRGLAVT GGVITSAGIV LAATFAVLGV LPLVFLAEVG FAVAFGVLLD TVVVRSVLVP
ALSHDIGRAI WWPSALSHAD R
//
