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Database: UniProt
Entry: A0A0K2YLN0_9NOCA
LinkDB: A0A0K2YLN0_9NOCA
Original site: A0A0K2YLN0_9NOCA 
ID   A0A0K2YLN0_9NOCA        Unreviewed;       531 AA.
AC   A0A0K2YLN0;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   05-JUL-2017, entry version 15.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:CRK53841.1};
GN   ORFNames=RHCRD62_70135 {ECO:0000313|EMBL:CRK53841.1};
OS   Rhodococcus sp. RD6.2.
OC   Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae;
OC   Rhodococcus.
OX   NCBI_TaxID=260936 {ECO:0000313|EMBL:CRK53841.1, ECO:0000313|Proteomes:UP000044872};
RN   [1] {ECO:0000313|EMBL:CRK53841.1, ECO:0000313|Proteomes:UP000044872}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RD6.2 {ECO:0000313|EMBL:CRK53841.1,
RC   ECO:0000313|Proteomes:UP000044872};
RA   Wang D.B., Wang M.;
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CVQP01000010; CRK53841.1; -; Genomic_DNA.
DR   RefSeq; WP_050066804.1; NZ_CVQP01000010.1.
DR   EnsemblBacteria; CRK53841; CRK53841; RHCRD62_70135.
DR   Proteomes; UP000044872; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000044872};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000044872}.
FT   DOMAIN      225    353       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      437    505       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     233    240       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   531 AA;  59209 MW;  217A85DF1F200F30 CRC64;
     MNEEPNTLAR VWVDVLAELT ADKSGQPLTK AQKAMLALVR PLTLAQGFAL LSVPSSFVQE
     AIERDLREPI LQTLNRHIDE GVEGLGVRIA PPTSEAQASV VTAPIPVVPE PEPLTPLRQS
     GESEAANTGT VSVEAFRRRR PGIGDADLFE PDPSEHDEID EDGEAIASVN ESWPSYFTKP
     PTTPPAASDG NSLNAKYTFD TFVIGASNRF AHAAAVACAE APARAYNPLF VWGSSGLGKT
     HLLHAAGHYS RRLFPGIRVR YVSTEEFTND FINSLRDDRK VAFKRRYRET DVLLVDDIQF
     IEGKEGIQEE FFYTFEALHN ANKQIVITSD RPPKQLATLE ERLRTRFEWG LITDVQPPEL
     ETRIAILSKK ARMDRLDVPH DVLELIASRL DRNIRELEGA LIRVTAFASL NRQALDLSLA
     EVVLRDLMPD ATPLEIDAAT IIAATSDYFG MAIEDLCGPG KTRPLAQARQ IAMYLCRELT
     DLSLPKIGNT FGRDHTTVMY ADKKIRKEMT ERRKVYDQVQ ELTARIKQRA R
//
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