ID A0A0K8P4C5_IDESA Unreviewed; 570 AA.
AC A0A0K8P4C5;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Cyclohexanone monooxygenase {ECO:0000313|EMBL:GAP37461.1};
DE EC=1.14.13.22 {ECO:0000313|EMBL:GAP37461.1};
GN ORFNames=ISF6_3316 {ECO:0000313|EMBL:GAP37461.1};
OS Ideonella sakaiensis (strain NBRC 110686 / TISTR 2288 / 201-F6).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Piscinibacter.
OX NCBI_TaxID=1547922 {ECO:0000313|EMBL:GAP37461.1, ECO:0000313|Proteomes:UP000037660};
RN [1] {ECO:0000313|Proteomes:UP000037660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 110686 / TISTR 2288 / 201-F6
RC {ECO:0000313|Proteomes:UP000037660};
RA Yoshida S., Hiraga K., Takehana T., Taniguchi I., Yamaji H., Maeda Y.,
RA Toyohara K., Miyamoto K., Kimura Y., Oda K.;
RT "Discovery of a poly(ethylene terephthalate assimilation.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GAP37461.1, ECO:0000313|Proteomes:UP000037660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 110686 / TISTR 2288 / 201-F6
RC {ECO:0000313|Proteomes:UP000037660};
RX PubMed=26965627; DOI=10.1126/science.aad6359;
RA Yoshida S., Hiraga K., Takehana T., Taniguchi I., Yamaji H., Maeda Y.,
RA Toyohara K., Miyamoto K., Kimura Y., Oda K.;
RT "A bacterium that degrades and assimilates poly(ethylene terephthalate).";
RL Science 351:1196-1199(2016).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the FAD-binding monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00010139}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAP37461.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BBYR01000047; GAP37461.1; -; Genomic_DNA.
DR RefSeq; WP_054021399.1; NZ_BBYR01000047.1.
DR AlphaFoldDB; A0A0K8P4C5; -.
DR STRING; 1547922.ISF6_3316; -.
DR OrthoDB; 9790219at2; -.
DR Proteomes; UP000037660; Unassembled WGS sequence.
DR GO; GO:0018667; F:cyclohexanone monooxygenase activity; IEA:UniProtKB-EC.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR020946; Flavin_mOase-like.
DR PANTHER; PTHR43098; L-ORNITHINE N(5)-MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR43098:SF3; L-ORNITHINE N(5)-MONOOXYGENASE-RELATED; 1.
DR Pfam; PF00743; FMO-like; 1.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Monooxygenase {ECO:0000313|EMBL:GAP37461.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:GAP37461.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000037660}.
FT REGION 550..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..570
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 570 AA; 62118 MW; 7346E666DE04C35C CRC64;
MSADVSLGAA RPSVGVHDLL IVGAGFAGMY MLHRARGLGL DATVLEAGDD VGGTWYWNRY
PGARCDIESF EYSYAFDEAL QQEWVWTERY APQAEILRYA QHVADRFGLR RDIRFRTRVV
SAHYDAAAQR WNVGTEAGDT LQARWVVMAT GCLSAARVPE LPGAADFRGR QLHTGRWPHE
PVSFAGQRVG VIGTGSSGIQ AIPVIAREAA QLVVFQRTPG YSLPAFNRPL PREALDEVKR
DYPALRKRAR ESMAGVAGYP VPTRSAFDVD EAERDRIYET HWRAGRTSIG RSFTDLLTDA
EANRTAADFV RAKIRASVAD PGLAETLLPR HAIATKRVCL DSGYYETYNR DNVRLVDLRR
TPIERLTPDG IRIAGEDIAL DAIVYATGYD AMTGALLAMD IRGRDGLALR EAWQAGPRTQ
LGLMTAGFPN LFFVTGPGSP SVLSNVIVCI EQHVDWIAGL LRALRSRGAG VVEPTLEAQD
AWVAHVNALA ARTLYMDADS WYLGANVPGK PRVFMPYVGG VGPYRRLCDQ IAADGYPGFR
FSAAGAPTEL SADPSAVPPA VPPAVPPAVP
//
