ID A0A0K8Q9B8_9MICC Unreviewed; 202 AA.
AC A0A0K8Q9B8;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 28-JUN-2023, entry version 19.
DE RecName: Full=3-methyl-2-oxobutanoate hydroxymethyltransferase {ECO:0000256|ARBA:ARBA00012618};
DE EC=2.1.2.11 {ECO:0000256|ARBA:ARBA00012618};
DE Flags: Fragment;
GN ORFNames=AHiyo6_31480 {ECO:0000313|EMBL:GAP56583.1};
OS Arthrobacter sp. Hiyo6.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=1588022 {ECO:0000313|EMBL:GAP56583.1, ECO:0000313|Proteomes:UP000037466};
RN [1] {ECO:0000313|Proteomes:UP000037466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hiyo6 {ECO:0000313|Proteomes:UP000037466};
RA Hiraoka S., Machiyama A., Iwasaki W.;
RT "Microbial genome analysis of tsunami-affected soil.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GAP56583.1, ECO:0000313|Proteomes:UP000037466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hiyo6 {ECO:0000313|EMBL:GAP56583.1,
RC ECO:0000313|Proteomes:UP000037466};
RX PubMed=26764021; DOI=10.1186/s12864-016-2380-4;
RA Hiraoka S., Machiyama A., Ijichi M., Inoue K., Oshima K., Hattori M.,
RA Yoshizawa S., Kogure K., Iwasaki W.;
RT "Genomic and metagenomic analysis of microbes in a soil environment
RT affected by the 2011 Great East Japan Earthquake tsunami.";
RL BMC Genomics 17:53-53(2016).
CC -!- SUBUNIT: Homodecamer; pentamer of dimers.
CC {ECO:0000256|ARBA:ARBA00011424}.
CC -!- SIMILARITY: Belongs to the PanB family.
CC {ECO:0000256|ARBA:ARBA00008676}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAP56583.1}.
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DR EMBL; BBUE01000459; GAP56583.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0K8Q9B8; -.
DR Proteomes; UP000037466; Unassembled WGS sequence.
DR GO; GO:0003864; F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0015940; P:pantothenate biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR InterPro; IPR003700; Pantoate_hydroxy_MeTrfase.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR PANTHER; PTHR20881; 3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR20881:SF0; 3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE; 1.
DR Pfam; PF02548; Pantoate_transf; 1.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:GAP56583.1};
KW Pantothenate biosynthesis {ECO:0000256|ARBA:ARBA00022655};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:GAP56583.1}.
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 202
FT /evidence="ECO:0000313|EMBL:GAP56583.1"
SQ SEQUENCE 202 AA; 21170 MW; D5CFC11C50FE7657 CRC64;
MSAEVPAPYG NGPTQPASPP SGGTKKPVAR IRTHHLQQAK ANGEHFAMLT AYEQYTAEIF
DQAGIEVLLV GDSASNNVFG NETSLPVTVD ELLPLCRAVA RSAKRALVVA DLPFGSYEVS
AEQAVASGVR FLKEGLAHAV KIEGGKYYAA TVRAMVQAGI PVMAHIGFTP QSEHSLGGYR
VQGRGDDAQR LIDDAVALAG AG
//
