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Database: UniProt
Entry: A0A0K8QCZ8_9MICC
LinkDB: A0A0K8QCZ8_9MICC
Original site: A0A0K8QCZ8_9MICC 
ID   A0A0K8QCZ8_9MICC        Unreviewed;       473 AA.
AC   A0A0K8QCZ8;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   05-JUL-2017, entry version 17.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AHiyo1_28440 {ECO:0000313|EMBL:GAP59525.1};
OS   Arthrobacter sp. Hiyo1.
OC   Bacteria; Actinobacteria; Micrococcales; Micrococcaceae; Arthrobacter.
OX   NCBI_TaxID=1588020 {ECO:0000313|EMBL:GAP59525.1, ECO:0000313|Proteomes:UP000063628};
RN   [1] {ECO:0000313|EMBL:GAP59525.1, ECO:0000313|Proteomes:UP000063628}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hiyo1 {ECO:0000313|EMBL:GAP59525.1,
RC   ECO:0000313|Proteomes:UP000063628};
RX   PubMed=26764021; DOI=10.1186/s12864-016-2380-4;
RA   Hiraoka S., Machiyama A., Ijichi M., Inoue K., Oshima K., Hattori M.,
RA   Yoshizawa S., Kogure K., Iwasaki W.;
RT   "Genomic and metagenomic analysis of microbes in a soil environment
RT   affected by the 2011 Great East Japan Earthquake tsunami.";
RL   BMC Genomics 17:53-53(2016).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; DF952471; GAP59525.1; -; Genomic_DNA.
DR   RefSeq; WP_059388864.1; NZ_BBUD01000593.1.
DR   Proteomes; UP000063628; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000063628};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000063628}.
FT   DOMAIN      164    292       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      376    445       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     172    179       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   473 AA;  53021 MW;  F0A8EFD6AA943BFD CRC64;
     MTVDEANHAN TVGSSWRRVL SLLEQDDRVT PRQRGFVILA QAQGLIGSTL LVAVPNELTR
     EVLQTQVKDA LDDALRSVFS DDIRCAIDVD TDLVPIHEEP APAVELSSVN DLAVESKPQP
     TPPSTSHEFG RLNPKYVFDT FVIGSSNRFA HAAAVAVAEA PAKAYNPLFI YGDSGLGKTH
     LLHAIGHYAR RLYSGIRVRY VNSEEFTNDF INSIRDDEGA SFKTTYRNVD VLLIDDIQFL
     AGKDRTLEEF FHTFNALHNN NKQVVITSDL PPKQLAGFED RMKSRFEWGL LTDIQPPELE
     TRIAILRKKA QSEGLSAPDD ALEYIASKIS SNIRELEGAL IRVTAFASLN RQPVDVALAE
     MVLKDLITDD GAQEITADQI LKQTAEYFKL SMEELCSKSR TRTLVTARQI AMYLCRELTD
     MSLPKIGQEL GGRDHTTVIH ADRKIRELMA ERRVIYNQVT ELTNRIKQQQ RDS
//
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