ID A0A0K9GZE9_9BACI Unreviewed; 305 AA.
AC A0A0K9GZE9;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=DNA-3-methyladenine glycosylase II {ECO:0000256|ARBA:ARBA00012000};
DE EC=3.2.2.21 {ECO:0000256|ARBA:ARBA00012000};
GN ORFNames=AC625_23455 {ECO:0000313|EMBL:KMY52109.1};
OS Peribacillus loiseleuriae.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Peribacillus.
OX NCBI_TaxID=1679170 {ECO:0000313|EMBL:KMY52109.1, ECO:0000313|Proteomes:UP000037146};
RN [1] {ECO:0000313|Proteomes:UP000037146}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FJAT-27997 {ECO:0000313|Proteomes:UP000037146};
RA Liu B., Wang J., Zhu Y., Liu G., Chen Q., Chen Z., Lan J., Che J., Ge C.,
RA Shi H., Pan Z., Liu X.;
RT "Genome sequencing project for genomic taxonomy and phylogenomics of
RT Bacillus-like bacteria.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-
CC methylguanine, 7-methylguanine and 7-methyladenine.; EC=3.2.2.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000086};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMY52109.1}.
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DR EMBL; LFZW01000001; KMY52109.1; -; Genomic_DNA.
DR RefSeq; WP_049683467.1; NZ_LFZW01000001.1.
DR AlphaFoldDB; A0A0K9GZE9; -.
DR STRING; 1679170.AC625_23455; -.
DR PATRIC; fig|1679170.3.peg.5255; -.
DR OrthoDB; 9785929at2; -.
DR Proteomes; UP000037146; Unassembled WGS sequence.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0008534; F:oxidized purine nucleobase lesion DNA N-glycosylase activity; IEA:InterPro.
DR GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd00056; ENDO3c; 1.
DR Gene3D; 3.30.310.20; DNA-3-methyladenine glycosylase AlkA, N-terminal domain; 1.
DR Gene3D; 1.10.1670.10; Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal); 1.
DR InterPro; IPR037046; AlkA_N_sf.
DR InterPro; IPR011257; DNA_glycosylase.
DR InterPro; IPR003265; HhH-GPD_domain.
DR InterPro; IPR023170; HhH_base_excis_C.
DR InterPro; IPR012904; OGG_N.
DR PANTHER; PTHR43003; DNA-3-METHYLADENINE GLYCOSYLASE; 1.
DR PANTHER; PTHR43003:SF12; DNA-3-METHYLADENINE GLYCOSYLASE; 1.
DR Pfam; PF00730; HhH-GPD; 1.
DR Pfam; PF07934; OGG_N; 1.
DR SMART; SM00478; ENDO3c; 1.
DR SUPFAM; SSF48150; DNA-glycosylase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000037146}.
FT DOMAIN 136..301
FT /note="HhH-GPD"
FT /evidence="ECO:0000259|SMART:SM00478"
SQ SEQUENCE 305 AA; 35414 MW; CC2A6BC16F5128CF CRC64;
MNWIDHGSYL EIYPPKEFNF EECLIFLGRS NQEVLHQTEG GSVYKLIKVN ESLILFKIGY
INASIKVEFP ISIPSIHSRK KVAEYIWEWF DLGQDLGGFY QVASRDKVLK KIAHKYYGLR
MMCIPDLFEA LVWAVIGQQI NLTFAYTLKK RFVEQFGECL TFEGEPFWLF PSFEKIASLN
VEDLRKLQFT ARKAEYIIGI AKAMINGELT KELLLQKQDD QQVQKSLMLT RGIGAWTADY
VMMKCLHYTS SLPIADVGLH NALKNLLGLE SKPTKEEIKE LAEDWKGWQA YATFYLWRSL
YDKNT
//
