ID A0A0K9PAE4_ZOSMR Unreviewed; 811 AA.
AC A0A0K9PAE4;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN ORFNames=ZOSMA_338G00190 {ECO:0000313|EMBL:KMZ65135.1};
OS Zostera marina (Eelgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Zosteraceae; Zostera.
OX NCBI_TaxID=29655 {ECO:0000313|EMBL:KMZ65135.1, ECO:0000313|Proteomes:UP000036987};
RN [1] {ECO:0000313|Proteomes:UP000036987}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Finnish {ECO:0000313|Proteomes:UP000036987};
RX PubMed=26814964; DOI=10.1038/nature16548;
RA Olsen J.L., Rouze P., Verhelst B., Lin Y.-C., Bayer T., Collen J.,
RA Dattolo E., De Paoli E., Dittami S., Maumus F., Michel G., Kersting A.,
RA Lauritano C., Lohaus R., Toepel M., Tonon T., Vanneste K., Amirebrahimi M.,
RA Brakel J., Bostroem C., Chovatia M., Grimwood J., Jenkins J.W.,
RA Jueterbock A., Mraz A., Stam W.T., Tice H., Bornberg-Bauer E., Green P.J.,
RA Pearson G.A., Procaccini G., Duarte C.M., Schmutz J., Reusch T.B.H.,
RA Van de Peer Y.;
RT "The genome of the seagrass Zostera marina reveals angiosperm adaptation to
RT the sea.";
RL Nature 530:331-335(2016).
CC -!- FUNCTION: Essential component of the vacuolar proton pump (V-ATPase), a
CC multimeric enzyme that catalyzes the translocation of protons across
CC the membranes. Required for assembly and activity of the V-ATPase.
CC {ECO:0000256|RuleBase:RU361189}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00009904, ECO:0000256|RuleBase:RU361189}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMZ65135.1}.
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DR EMBL; LFYR01001074; KMZ65135.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0K9PAE4; -.
DR STRING; 29655.A0A0K9PAE4; -.
DR OMA; YHILNYF; -.
DR OrthoDB; 1967517at2759; -.
DR Proteomes; UP000036987; Unassembled WGS sequence.
DR GO; GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IBA:GO_Central.
DR GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR GO; GO:0051117; F:ATPase binding; IBA:GO_Central.
DR GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR GO; GO:0007035; P:vacuolar acidification; IBA:GO_Central.
DR InterPro; IPR002490; V-ATPase_116kDa_su.
DR InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR PANTHER; PTHR11629:SF63; V-TYPE PROTON ATPASE SUBUNIT A; 1.
DR PANTHER; PTHR11629; VACUOLAR PROTON ATPASES; 1.
DR Pfam; PF01496; V_ATPase_I; 1.
DR PIRSF; PIRSF001293; ATP6V0A1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrogen ion transport {ECO:0000256|ARBA:ARBA00022781,
KW ECO:0000256|RuleBase:RU361189};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU361189};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361189};
KW Reference proteome {ECO:0000313|Proteomes:UP000036987};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361189};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361189};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361189}.
FT TRANSMEM 411..435
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 456..473
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 536..554
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 574..591
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 625..643
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 747..768
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT COILED 94..128
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 811 AA; 93036 MW; 58A1CBB7C897941E CRC64;
MIGARHPMDM IRSEAMQLVQ FIIPIESSHL TVSYLGELGL VQFRDLNANK NLFQRTHANQ
IKRCGEMGRK LRFFKDHMAK AGILPSVLSE MSQMTQAHTD FDELEAILSE LEDDLIRVNA
NNLKLLRTYN EHLEYMLVIQ KVGEFLYAKQ NLTAALRSQI HDTDRSEMIT DPSKQIKLGF
VSGLIPKEKT MAFERTLFRA TRGNMFLKQA AVENLVTDPV SGDKIAKNVF VAFYSGERAK
EKIIKICDSF GANRYPHADD LERRREIIEE VSRKISELKV TVDVGLQHRE NLLKHINDQF
AQWNLLVKKE KSVYHILNMF SFDVTKKCLV AEGWSPIFAS NQIQSILQKA TIDSNSQIGS
IFQVLHTKES PPTYFHTNKF TMAFQEIVDA YGVAKYQEIN PAVYTIITFP FLFAVMFGDW
GHGICLLLIT LYFIVREKKL SSQKLGDITE MIFGGRYVIL MMALSSIYTG LIYNEFFSVP
FDLFGKTAYA CSDTSCINAY TQGLTKVRQT YSFGVDPQWH GSRTELPFLN SLKMKMSILL
GVTQMNLGII LSYFNGNFFK NNLNIWHQFV PQMIFLNSLF GYLSILIIVK WCTGSKADLY
HVMIYMFLNP TDELGENQLF IGQKILQVIL LLFAVVSVPW MLFPKPFLLK RQHQARHQRR
DFAMETLFTV DNDTIELNPD HDSNSDKEFE FSEVFVHQLI HTIEFVLGAV SNTASYLRLW
ALSLAHSELS SVFYDKVLIL AWGYKNVFII IIGIIIFLFA TIGVLLVMET LSAFLHALRL
HWVEFQNKFY EGDGYKFAPF SFALLSEGGD D
//
