ID A0A0K9XC06_9ACTN Unreviewed; 321 AA.
AC A0A0K9XC06;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=GntR family transcriptional regulator {ECO:0000313|EMBL:KNB50167.1};
GN ORFNames=AC230_26095 {ECO:0000313|EMBL:KNB50167.1};
OS Streptomyces caatingaensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1678637 {ECO:0000313|EMBL:KNB50167.1, ECO:0000313|Proteomes:UP000037288};
RN [1] {ECO:0000313|Proteomes:UP000037288}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CMAA 1322 {ECO:0000313|Proteomes:UP000037288};
RA Santos S.N., Gacesa R., Taketani R.G., Long P.F., Melo I.S.;
RT "Draft genome sequence of Streptomyces sp. CMAA 1322, a bacterium isolated
RT from Caatinga biome, from dry forest semiarid of Brazil.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNB50167.1}.
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DR EMBL; LFXA01000017; KNB50167.1; -; Genomic_DNA.
DR RefSeq; WP_049718702.1; NZ_LFXA01000017.1.
DR AlphaFoldDB; A0A0K9XC06; -.
DR STRING; 1678637.AC230_26095; -.
DR PATRIC; fig|1678637.3.peg.5571; -.
DR Proteomes; UP000037288; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR004111; Repressor_TetR_C.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR44846; MANNOSYL-D-GLYCERATE TRANSPORT/METABOLISM SYSTEM REPRESSOR MNGR-RELATED; 1.
DR PANTHER; PTHR44846:SF1; MANNOSYL-D-GLYCERATE TRANSPORT_METABOLISM SYSTEM REPRESSOR MNGR; 1.
DR Pfam; PF00392; GntR; 1.
DR Pfam; PF02909; TetR_C_1; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000037288};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..71
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
FT DOMAIN 95..155
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 118..137
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 321 AA; 34555 MW; CC8A495A886BE9EF CRC64;
MTPPPYLRIV EDIRHRIATG ELAPGDRVPS TRRIAQDWGV ALATAARALA TLQQEGLIRA
RPRVGSVVAP REQAARRAAA GGTGGAAGAA GADRDLTRER IVRAAIGIAD AEGLGALSMR
GVAAKLGVST MSTYRYVDGK DALVLLMADA AFGEAEFPGE PPEGWRARVE LAARTLWSLY
RRHPWLAHLG PVTRPLALPN LIAYGDWLLA ALGELALDVR TRFDLHVLVY SHVVGLAAHL
EDERRAEAAT GLTDEEWMDR QEAGFAELAA SGRYPAFSEV VEELRATGGY DLRLDELFEF
GLQRLLDGIA VGLADPGTAR R
//
