ID A0A0L0BP76_LUCCU Unreviewed; 594 AA.
AC A0A0L0BP76;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Putative Bardet-Biedl syndrome 4 protein {ECO:0000313|EMBL:KNC21821.1};
GN ORFNames=FF38_03177 {ECO:0000313|EMBL:KNC21821.1};
OS Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Calliphoridae; Luciliinae; Lucilia.
OX NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC21821.1, ECO:0000313|Proteomes:UP000037069};
RN [1] {ECO:0000313|EMBL:KNC21821.1, ECO:0000313|Proteomes:UP000037069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS {ECO:0000313|EMBL:KNC21821.1,
RC ECO:0000313|Proteomes:UP000037069};
RC TISSUE=Full body {ECO:0000313|EMBL:KNC21821.1};
RX PubMed=26108605; DOI=10.1038/ncomms8344;
RA Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R., Murali S.C.,
RA Hughes D.S., Lee S.F., Perry T., Stroehlein A.J., Ansell B.R.,
RA Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L., Chao H., Dinh H.,
RA Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M., Ioannidis P.,
RA Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H., Kotze A.C.,
RA Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT "Lucilia cuprina genome unlocks parasitic fly biology to underpin future
RT interventions.";
RL Nat. Commun. 6:7344-7344(2015).
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium membrane
CC {ECO:0000256|ARBA:ARBA00004309}.
CC -!- SIMILARITY: Belongs to the BBS4 family.
CC {ECO:0000256|ARBA:ARBA00023778}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC21821.1}.
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DR EMBL; JRES01001578; KNC21821.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0BP76; -.
DR STRING; 7375.A0A0L0BP76; -.
DR EnsemblMetazoa; KNC21821; KNC21821; FF38_03177.
DR OMA; AGTNIDW; -.
DR Proteomes; UP000037069; Unassembled WGS sequence.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR44186; -; 1.
DR PANTHER; PTHR44186:SF1; BARDET-BIEDL SYNDROME 4 PROTEIN; 1.
DR Pfam; PF12895; ANAPC3; 1.
DR Pfam; PF13181; TPR_8; 2.
DR SMART; SM00028; TPR; 9.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 5.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Reference proteome {ECO:0000313|Proteomes:UP000037069};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 73..106
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 152..185
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 186..219
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 254..287
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 322..355
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 370..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 528..565
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..553
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 594 AA; 67050 MW; C2DD54A36E00ED1A CRC64;
MMSAGTNIDW LLHIYFARKD FERCKKLIDR ELYRHLNPEY LYFVKGLIDR EEGNNIEALR
NLQKSLKLNS QNIEIYKEIG KTLFMMGRYN QSLSIFREAE ELSTRLDHEI FHFIGELLLR
SAAARNQYEL AHQEELEAKT YFQKAVQTGK KLESFQRLAE IHRKEKEYNK AIEVLENCLL
LSPENTDVLT EIGVLYLKLN ETQKAFDRLL EVIQFDKNCL RGLMAFGAIL QSRNDVDGAL
GKYREIAALK PDIAELWNNI GLCFFKKQKF IVAISSLRKA IWLSPLNYNA LYNLSLIYIT
AQQYASAFHT LAAAINLRKD NAECYMLLGI CLRKLEDFDN AFTAFERASA ISAAAFATST
TSSSSAATAT ASKSATNNQN ANSKSTTGGS TSNTSHNPLI HLNFALFCYE TGRLAMATEQ
YNRFVGCAQD LMLLPTEYKF QATKLKSLLK ISSSHILSCG DTANTSATAV LASDVIDIET
ADLATTTTTT TTTAAKAADD DDASVSNIYN YVNVIERRNN IPDDFAEEDE KGNVKEQRQQ
RLNNDNSYND KYNVNADNDK DKDNNDFARV SEDNDTMFVK QKSKIPLEVN AVVN
//
