ID A0A0L0C2F2_LUCCU Unreviewed; 500 AA.
AC A0A0L0C2F2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Segmentation protein Runt {ECO:0000313|EMBL:KNC26505.1};
GN ORFNames=FF38_08615 {ECO:0000313|EMBL:KNC26505.1};
OS Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Calliphoridae; Luciliinae; Lucilia.
OX NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC26505.1, ECO:0000313|Proteomes:UP000037069};
RN [1] {ECO:0000313|EMBL:KNC26505.1, ECO:0000313|Proteomes:UP000037069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS {ECO:0000313|EMBL:KNC26505.1,
RC ECO:0000313|Proteomes:UP000037069};
RC TISSUE=Full body {ECO:0000313|EMBL:KNC26505.1};
RX PubMed=26108605; DOI=10.1038/ncomms8344;
RA Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R., Murali S.C.,
RA Hughes D.S., Lee S.F., Perry T., Stroehlein A.J., Ansell B.R.,
RA Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L., Chao H., Dinh H.,
RA Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M., Ioannidis P.,
RA Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H., Kotze A.C.,
RA Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT "Lucilia cuprina genome unlocks parasitic fly biology to underpin future
RT interventions.";
RL Nat. Commun. 6:7344-7344(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC26505.1}.
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DR EMBL; JRES01000984; KNC26505.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0C2F2; -.
DR STRING; 7375.A0A0L0C2F2; -.
DR EnsemblMetazoa; KNC26505; KNC26505; FF38_08615.
DR EnsemblMetazoa; XM_023435488.2; XP_023291256.1; LOC111674826.
DR OMA; TPYAMPQ; -.
DR OrthoDB; 2881451at2759; -.
DR Proteomes; UP000037069; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR Gene3D; 2.60.40.720; -; 1.
DR InterPro; IPR000040; AML1_Runt.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR012346; p53/RUNT-type_TF_DNA-bd_sf.
DR InterPro; IPR013524; Runt_dom.
DR PANTHER; PTHR11950; RUNT RELATED; 1.
DR PANTHER; PTHR11950:SF31; SEGMENTATION PROTEIN RUNT; 1.
DR Pfam; PF00853; Runt; 1.
DR PRINTS; PR00967; ONCOGENEAML1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS51062; RUNT; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000037069};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 54..182
FT /note="Runt"
FT /evidence="ECO:0000259|PROSITE:PS51062"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 460..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 259..276
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..495
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 500 AA; 53384 MW; AFFE70BD7789B7D5 CRC64;
MHLPAGPTMV ATPAQAMPTN NNNTNSASST GSSTPDTTSN AAKMPSSMTD MFASLHEMLQ
EYHGELAQTG SPSILCSALP NHWRSNKSLP GAFKVIALDD VPDGTLVTIK CGNDENYCGE
LRNSTAIMKN QVAKFNDLRF VGRSGRGKSF TLTITIATYP VQIASYTKAI KVTVDGPREP
RSKQSYGYPH PGAFNPFMLN PAWLDAAYMT YGYADYFRHQ AAAAAVHHPA LAKTSPLPTG
QTVVPPPSAA GSPNDYHHPS QITPPPAGAP AVNPASMIPS PPGSNYSMPQ FPFNPVAAAA
AAAAAQAHPD LLHPHQKAAH PHAFHPYNLA GLRARPNHMH NTSLGSHSST EHISPAHISP
ASSRPSSSSP THAALNNKFN TSVETSSLHE QSASDADSDD EQIDVVKSAF VPILRPQIPS
LNGSIEDLDK SIDSTRSSPT QHITLPPRAR CELKAPSSMK PYFHETSSQH SRQSSPETTL
PAATKLKSAA NTQKTVWRPY
//
