ID A0A0L0C4Z7_LUCCU Unreviewed; 601 AA.
AC A0A0L0C4Z7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Runt domain-containing protein {ECO:0000259|PROSITE:PS51062};
GN ORFNames=FF38_08612 {ECO:0000313|EMBL:KNC26504.1};
OS Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Calliphoridae; Luciliinae; Lucilia.
OX NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC26504.1, ECO:0000313|Proteomes:UP000037069};
RN [1] {ECO:0000313|EMBL:KNC26504.1, ECO:0000313|Proteomes:UP000037069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS {ECO:0000313|EMBL:KNC26504.1,
RC ECO:0000313|Proteomes:UP000037069};
RC TISSUE=Full body {ECO:0000313|EMBL:KNC26504.1};
RX PubMed=26108605; DOI=10.1038/ncomms8344;
RA Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R., Murali S.C.,
RA Hughes D.S., Lee S.F., Perry T., Stroehlein A.J., Ansell B.R.,
RA Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L., Chao H., Dinh H.,
RA Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M., Ioannidis P.,
RA Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H., Kotze A.C.,
RA Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT "Lucilia cuprina genome unlocks parasitic fly biology to underpin future
RT interventions.";
RL Nat. Commun. 6:7344-7344(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC26504.1}.
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DR EMBL; JRES01000984; KNC26504.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0C4Z7; -.
DR STRING; 7375.A0A0L0C4Z7; -.
DR EnsemblMetazoa; KNC26504; KNC26504; FF38_08612.
DR EnsemblMetazoa; XM_023440664.2; XP_023296432.1; LOC111679154.
DR OMA; PRYHTNT; -.
DR Proteomes; UP000037069; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR Gene3D; 2.60.40.720; -; 1.
DR InterPro; IPR000040; AML1_Runt.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR012346; p53/RUNT-type_TF_DNA-bd_sf.
DR InterPro; IPR013524; Runt_dom.
DR PANTHER; PTHR11950:SF49; PROTEIN LOZENGE-RELATED; 1.
DR PANTHER; PTHR11950; RUNT RELATED; 1.
DR Pfam; PF00853; Runt; 1.
DR PRINTS; PR00967; ONCOGENEAML1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS51062; RUNT; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000037069};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 84..212
FT /note="Runt"
FT /evidence="ECO:0000259|PROSITE:PS51062"
FT REGION 1..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 373..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 601 AA; 63127 MW; E5EC9C1866889F37 CRC64;
MHLTTTTTNG TANTNNTATA NNNNNNNNSQ NNNNNSSSNT NSNNNNNSSN GNNNSTEQNT
PPTAAQLLNE AYTKMTSDIL AERTLGDFLT EHPGELIRTS SPLFVCTVLP PHWRSNKTLP
VAFKVVSLGD IMDGTMVTVR AGNDENYCAE LRNSTAVMKN QVAKFNDLRF VGRSGRGKSF
TLTITVSTNP PHIATYNKAI KVTVDGPREP RSKTRQQQQF HFAFGQRPFH FSTDPLSGFR
MPPIGNCQSA SNTHWGYGSA TAYSPYLASS GLSSCTTPTS AQFNNPALGF SCSSNEQPNN
QDFTGASNRD CVPMLPDSTA SDLDQHLSNL VGSTTGQMTH HSLLGSTGQT AISSTVNGGA
VAGTNSILVP RYHNTNNDYN VHSSQNGPRS LSDSSQAESP VQEDLLSTNT PNLGGTNGNA
TANGGTNSNS NGSANNSLVG ANQNFSGIVN QTQNPAAYGG ATGTGVGVGG GHTGAAGAGC
NGSLYPVLPA SLLYSQLYTA ANQSHGFHSH ALPSHTSPNS TVHGELQSVM DHISNVGVRQ
QHNIMSGGGV THPGDLTLIG NCGASVRNIE DGNTNRQLTA LAAHRGHHNP ADNGGSVWRP
Y
//
