ID A0A0L0CF49_LUCCU Unreviewed; 3690 AA.
AC A0A0L0CF49;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
DE Flags: Fragment;
GN ORFNames=FF38_01558 {ECO:0000313|EMBL:KNC30842.1};
OS Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Calliphoridae; Luciliinae; Lucilia.
OX NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC30842.1, ECO:0000313|Proteomes:UP000037069};
RN [1] {ECO:0000313|EMBL:KNC30842.1, ECO:0000313|Proteomes:UP000037069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS {ECO:0000313|EMBL:KNC30842.1,
RC ECO:0000313|Proteomes:UP000037069};
RC TISSUE=Full body {ECO:0000313|EMBL:KNC30842.1};
RX PubMed=26108605; DOI=10.1038/ncomms8344;
RA Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R., Murali S.C.,
RA Hughes D.S., Lee S.F., Perry T., Stroehlein A.J., Ansell B.R.,
RA Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L., Chao H., Dinh H.,
RA Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M., Ioannidis P.,
RA Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H., Kotze A.C.,
RA Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT "Lucilia cuprina genome unlocks parasitic fly biology to underpin future
RT interventions.";
RL Nat. Commun. 6:7344-7344(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC30842.1}.
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DR EMBL; JRES01000487; KNC30842.1; -; Genomic_DNA.
DR STRING; 7375.A0A0L0CF49; -.
DR EnsemblMetazoa; KNC30842; KNC30842; FF38_01558.
DR OMA; EAIVLNC; -.
DR Proteomes; UP000037069; Unassembled WGS sequence.
DR Gene3D; 2.60.40.10; Immunoglobulins; 6.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR45080; CONTACTIN 5; 1.
DR PANTHER; PTHR45080:SF8; WRAPPER_REGA-1_KLINGON HOMOLOG; 1.
DR Pfam; PF07679; I-set; 6.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF48726; Immunoglobulin; 7.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000037069}.
FT DOMAIN 196..276
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 297..384
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 399..473
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 497..581
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 596..674
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 856..949
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2370..2703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3181..3406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3425..3444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3450..3490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3563..3690
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1463..1524
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1566..1620
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2046..2080
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2923..2988
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 856..870
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 871..914
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 917..931
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2370..2391
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2404..2589
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2602..2635
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2646..2660
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2674..2694
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 3690
FT /evidence="ECO:0000313|EMBL:KNC30842.1"
SQ SEQUENCE 3690 AA; 416872 MW; E0C930527B6F79BD CRC64;
MGNGCSKCCK CNDHKNYHGT LSSSSSIYRK RSRGEIPIYN SDRFRITKTS TAVQLAVEHV
QREDAGHYTL FAKTKSNDVI RKDVQLIVED RSTGDDPPVF LRRLLDLQVR VGSSTRLITE
IRSSSDVKLT WFRNDRRVCE SDRIKEVHEG NFHYLEINPV VVEDGGQWMV MAENFSGRNS
CISNLTVLVP KAYKAPEFIE ELRAILTQQG TVSLECKVVG VPTPQLRWFK DSKEIKAGDV
FALTANADDP TSLGTYTCEA VNCVGKAYSS SKLHVVGRGS REGSLKPADS ATNTAPPPIF
TNELKNASVR IGDTIILGCQ VAVPPWPQSV VWYNKNGRVE SGDRYKYIED GLGVYMIAVK
PSEACDEGEW KCVVTNEESC VGISSCVVDM EIPKNYRKPR FMESLRAVLT EEGLVSFECK
VVGFPTPQLK WFKDGQELKP GDVYQLTGTN SLGTYCCIAK NCMGETSSIA VLTVEDIQNQ
LNDEERLTFA TSTSQPPKFL MGLKSEETKI NEPYQFTVKV EATPDPLLSW FRDELPIESN
DRYNHYRGEE NNWHLDIRNL EFIDQAEWKC VAVNDFGTTV TSCFLKLQIP RHYKKPRFLE
CLRAVLTEEG AVNLECKVIG VPQPVLKWYK DGVELKPGDI HKIISGQDGT CCLGTYTCEA
RNCMGVVASS AALLGFEDDY SKQESKQQNE LQRNFSLSTI QEEHTSQLYE TPQGDITITE
RGDVSFSFDG KEVSVSLYET PDLTEEEALK IVEMYADQIS EHVTEHNVVE LPPLRFVKET
SQSGKLLMEA VVIDISPEYF SHEEDLRTEA GMDDISINEI TIHGSSLKDD EELDRQTEDF
ARTSFEKMEE ELSLTAPIRK RKKSKPTETE EFFSFSKASD GSVDENTSEL QTFASAQMSK
MESLENSKSL SESIQAPARK KGKKQSDSES SKTTENEAQL QDISGAVGDG LKVTSDKPLK
VVSNEADIER NLKSLLPLAK LLKVLDGHLN AVESEVIQQS VMLMTPSSAD QSIAIIKNII
DPISQIQSKL KVYSGETPLD ALFETMNDDI RSLHVALQVI EKCVEIDETG TTLIQRTSVC
IIDSIADHLI KALDEVKMVS NMFENESLKS NLQLTVDDIK QGLEITKDTI KSQALLQEAQ
EIEATKHFTE TVAKLQDIPE PLPFAKVAEA NLPKYSESVT NICEPVLRIQ AALEKVENEL
TLEESDEDIY KKVHEKIMHN LVEPINELQA VVAEIEGKVS SLSGTDSIEQ KVNMAILDIV
SPPLFELNKG LEIIQQQPSH NIEAGKLTVS TVESMVPPLQ EIQNGLAQLS QDILSGQLND
DQLMDTDDLK KLLQSLAQAV LHLESNIDNI TSRLPQNVSM SLSKLREEIS SLIGQVIDKD
IDKYHLTVLE NIKKPIDELN YCIRQIEQKS ISGSLTDLVD PLHSLNDKVK MSQEVLQLST
TKQNFDIVET LDKMRNLIKH IEIDIEENEF KNMQKEIALD EEQAIKDNNL FLTMRQEMEM
RIELEESLKE IEKLNNNIKY LQENTYLDKE LKSQFGELAK PFEQVIDILT NKESLERGQH
SLQSSLNILR NTAKNCESLN QSLEKLKAVK SKNEFSKIFY TNCRTALEEL KATIDQLEYN
DVTATPVVTA FNKILVALEN IIPKLVTETA VEDLSTLEEV SALKSAAESL PLDSDRASLP
KDSKEEISAG PLKSFEEKKQ QVDELLGQLK NSIASVLAHC NDYDMGSLRI EAVEQMKATV
NKMTDFKQCL EQTLQPHVLD VVQTSSECTD LRTMAEAVCS LENCALQIQE YIDNFDVKDL
SGDEISELKT MAQPLKELVE GVKVFYNQEL EQVETMNTLS AVSMSSAKVL QSLRPYVLAV
HEHQALETLE SLADTQTFSH LKEFVQPLRE LEKAAICTEE NLMLSQMSNL SEQTSLEVLK
TWAKPLLSLK EAIVNVKQEQ AFSALEEYPA FRALKEKSSI LFNLLKYCEN FDAQIFENIE
DLSSLNISHI KSYAESATVS AQELMEPAKT HAQEVKTFDL KDCVKGGIKQ IEECLHNTKQ
IQDFEVTSLE DIMQELKNDL QNMENNLLKS NEKTEDLIVK ETKVAKTMFK LKECLVHTYE
ATDLETGLED IEKTFEDLLQ AMPSLELQLA LEMKEKIILG FSEFIVTCLQ TTEQQQQQSF
ETLIQPFRNL METVDIISKL NKIDVEPSSS VMIQLQTQLM TAFRALNDVS EKSNQEILPN
LLKTQNTLVS IYDFIENNEG NLRIIELLQE IDYLTPELRE IKDILASMQM QLLLENVNSA
QLFLMEIHEG LLQNNALVHA FMQDNKDTVE CLKNLLNKVE NKLHSKTVYE VEQEETVGIL
RDLLNNLKAN MARVKEIHLG EIETELEQKD VSEAKKTDQK KKQKVDKPIE QKQGENQNVQ
IEDKPVQLEE ESIKKEEQAK VKAESEKETQ KKAEVEASEQ TKTKPETQKK DEQKDIETDL
SKPQDIGQKA EEKDVDAATK ANEKAPMKAE QKDVEPAAKL VESNEPSKAK LEEEETPKKD
EQKETKTAKA KLESDEETSK KAEQKDVDTA AKAEEKAEKK DVEPAAKLVE ATEPVKAKPE
EETPKQDEQM DVDTTSTLVE ESGKETPKKV EQMDVDTSTK AEEKAQKKAE QKDVESAANL
VKTAEPVKAK PEEEPLNKNE PMDVDTALSL VEEPKVETPK KAEQKNDDAT SVLAEEAKPE
PPELTPLMKN VLQLINTNKQ YLETIKSKKV KQSTSEFVKS VMDNLKELQL AIEVDTPTNL
EDRLFLPLFK TKQLITYAAN TVSTDEITHN VLENLKHIML NIINDNDKLR KSILYEVVEA
VKPNVSQILE KIDSQPKKSK IIQKAAESLN QIVLEINNIY QNNLGNLETS STSFKALKSA
LSQLNEVTEE ISAIKPNVLN TNKLNRLMEK LDKSDIKDAL EILLDLENMK EMFEQLLETI
QSQSLMQHKP IEETVANALD VIGDNSDLED IKKDLQETLD SSNNEQKRKC IFKLREHIVH
TYDGGLNEEL ENVIDSILGN NSDLIESINA EYLKNINDNF NPICKQIDEV TTEPWHGKLT
GLTTKLLNIQ NIADRLKTVK DFEKSSINSI ELQKNLMDIF VLFDDMLEIA TSPLNTDVEK
VKSLALKQYD SIENSTVNIK TLQAYENMLD MCKLIKIVVE KVCEKSKSQE MEISVEELEE
KQVETKKAEE KELKTTKDKA EVSEVKAEKL EEKKVEAEAK KAEEKDLRTT KEKAEVSEVK
AEKLEEKKME AEAKKAEEKE LKTTKEKAEV SEVKAEKVEE MKVEDEAKKA EEKDLKTTKE
KAEVSEVKAE KLEEKKMEAE AKKAEEKELK ATKEKAEVSE VKAEKLEEKK VEAESKKAEE
KDLKTTKEKA EVSEVKAEQL EEKKVEAEAK KAEEKELKTT KEKAEVSEVK AEKLEEMKME
AEAKKAEEKE LKTTKEKAEV SEVKAEKIEE KKMEAEATKA EEKELKTTKE KAEVSEVKAE
KLEEKKMEAE ANKVAEMDLK TTKEKAEVSE VKAEKLEEKK MEAEAKKAAE MDLKTTKEKA
EVSEVKAEKL EEKKVEAEAK KAEEKELKAT KEKAEVSEVK AEKLEEKKME AEAKKTEEKD
LKTTKEKAEV SEVKAEKLEE KKMEAEAKKV EEKELKTTKE KAEVSEVKTE KVEEMKVEAE
AKKAEEKDLK TTKEKAEVSE VKAEKLEEKK
//
