ID A0A0L0D241_THETB Unreviewed; 980 AA.
AC A0A0L0D241;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Atypical/ABC1/ABC1-B protein kinase {ECO:0000313|EMBL:KNC46419.1};
GN ORFNames=AMSG_02873 {ECO:0000313|EMBL:KNC46419.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC46419.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC46419.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC46419.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL349442; KNC46419.1; -; Genomic_DNA.
DR RefSeq; XP_013760710.1; XM_013905256.1.
DR AlphaFoldDB; A0A0L0D241; -.
DR STRING; 461836.A0A0L0D241; -.
DR EnsemblProtists; KNC46419; KNC46419; AMSG_02873.
DR GeneID; 25562521; -.
DR eggNOG; KOG1235; Eukaryota.
DR OrthoDB; 177137at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd13969; ADCK1-like; 1.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR InterPro; IPR004147; ABC1_dom.
DR InterPro; IPR045307; ADCK1_dom.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR43173:SF28; AARF DOMAIN-CONTAINING PROTEIN KINASE 1; 1.
DR PANTHER; PTHR43173; ABC1 FAMILY PROTEIN; 1.
DR Pfam; PF03109; ABC1; 1.
DR Pfam; PF13517; FG-GAP_3; 2.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KNC46419.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|EMBL:KNC46419.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..980
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005537169"
FT TRANSMEM 923..944
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 558..801
FT /note="ABC1 atypical kinase-like"
FT /evidence="ECO:0000259|Pfam:PF03109"
SQ SEQUENCE 980 AA; 106755 MW; 04DB525E0B8E85AC CRC64;
MYASIEVSVV AVVLLGVVSL GMGASVRDHF PRTSEFVTAA CSGYNGRLAL ADMNNDGDVD
VLMGCGDSLT WIENSGDDTF STIIRTISID QNPVPAAADY DRDGDQDVIV GKTAGSDDFL
IVRNGTTSTG TAFPFAGWVL PVPGPQSPHV WKQVEPVDLN KDGWMDVVYA SDTVIECRTI
AAGDMDNDGK TDLVFVKEEV AGGVYVLVNT GPISSSATSA WGDGTFIRSL EHAMSLGIAD
LNEDSILDIA VTTFSFTLVD NNYPANFTKD AIDTVQASSV WIIEGTGSAA SFLTPVELNQ
RAYGPALVGD VTGDGLADIL IPSLRALSTV YVLPQAQLVK SACAGKITLF NITASEGVFK
FEHGKVGTAT ESASDEDCVF KIEAVSDVVL SVRAAIQRST KSSAYGVLQL FDRPDGRGEA
DVSITASSGQ APAFIPTTSI MSLRWVAPNS EGAAFTVEVT ASPRQPSTNP QAVRGGSRTV
RTFATAAVIG LDYKWSLHDL EYRTEAYIAK REEVHGRTAE RLLGLCKANQ GFYIKAAQTV
ASMQMGVPKQ VTSKLRVLQD SAPFKELADV LGTFEAEFGA SPHELFAEFD EQPFAAASLA
QVHKAVTHDG QRVAVKVQHA GLEDLITTDL WAMRTIASIM PFFFEDLELG WLVTEVEENI
AKELDFVREG QSAERVAASF ADMPHVRIPG IVWASSSRRV LTMEFMDGFS ISNEAQLEEQ
GVDRAQLTKL LLDTFSRMIF CTGFIHCDPH AGNLLVHKNA ETGALDLVLL DHGLYRELDD
EFRHNYCKLW KALVTYDGEL LDEAADGLGV PQYKFIFPLI LTYRPWSRSK DAAPGAGLSE
DEARKLREDM RKTSVAEVFK FLEDLPRDML LVFRSQDLVR SINKSLGGSS LDRFRVFVRA
AISGLYLYRN GEYAPPGWRD WFAYHWTMAG LELGGAIVAF GLWLGSMWRR VRSAIVGDGD
RDAEGGEVLD KFRKFEAKQG
//
