ID A0A0L0DB57_THETB Unreviewed; 1533 AA.
AC A0A0L0DB57;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
DE Flags: Fragment;
GN ORFNames=AMSG_04983 {ECO:0000313|EMBL:KNC48538.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC48538.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC48538.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC48538.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL349451; KNC48538.1; -; Genomic_DNA.
DR RefSeq; XP_013758645.1; XM_013903191.1.
DR EnsemblProtists; KNC48538; KNC48538; AMSG_04983.
DR GeneID; 25564493; -.
DR eggNOG; KOG2301; Eukaryota.
DR OMA; VCENISR; -.
DR OrthoDB; 5403296at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR Gene3D; 1.10.287.70; -; 2.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR46726; TWO PORE CHANNEL 3; 1.
DR PANTHER; PTHR46726:SF1; TWO PORE CHANNEL 3; 1.
DR Pfam; PF00520; Ion_trans; 2.
DR SMART; SM00054; EFh; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 681..699
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 711..730
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 778..804
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 825..847
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 897..921
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1044..1066
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1078..1107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1128..1151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1171..1191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1212..1236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 974..1009
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 148..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 281..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 346..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 385..535
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 571..618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1260..1285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1412..1533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..50
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..88
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..171
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..299
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..416
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 427..452
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1449..1501
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KNC48538.1"
SQ SEQUENCE 1533 AA; 167106 MW; 79CBC065979F052B CRC64;
MAELDRDGAR EAIERIRANR AQPPLPRTRS RSRSRARSRS RARSRSRARS RSRSCARDGY
TQQAPSSDDS MLSQSRWRSR QASSSQSSAP PPPSLPPLPT AGPRFVADSS DSEPLVVRVQ
RDGDNSELFS SLDSSAISHS HASVASARGA MLSSGSRSHS PVGSSESWDM TCSRRPDAAQ
ATVGSTLRSL HATEGGGKPL PPARFAQLSL VAPRASGTAG VVEAVRRIRR APTALHTRKL
QRRQTASVSP SREQSAALLA QAARADIGHR GSVQLEAVPS LEHSHHHHRH RHRHHHGHSS
PRSPDNLAAR ADTLLKQRLP QTKRDSLVAS PDLVRDLIKL EDKALARRSS LSRPIAQQPT
EASVAAMATK GEHNRQLLLQ IRPHRQDSDS DELSQSPSLP APSDKLPRAQ TSSSRHHLVP
RRPEVSGGSG SSRNSSRSPR TETCSRISPR SPNSSVRRRR RRSTSISVAG TAGPVLLVPP
ASPAQSSRPL PPQRLPSAKS FTALTPGKAD AKIRQLKRGE TKTTLKPPNS AVKAKDTARL
QNLHQHLRES GVDPTELDQL IVQKHLNKLP SADSFSGLRS KNRSRNRNDS NDPTSPACAD
LPSIVSDTGS ASSDSDNESS AYAYSYSYSY DVAPVLTSEQ HKEALELAGA YILDAIHGRP
PKLTRTSPAQ MRVYRFQHTR GWNYFLYFVV LFQMCLVFGE PAQTADATLP LHLLLPELFC
IVVYGIDLGM ELYHSGTARF FRPPSMLSES KGHTPPPGLC ARLLAASMPE WLSRVSWVLV
QSVIVVVITA DVLLHISVEA VPFMRVSRLL RSLQLFRAKV LRKNFVVLIR TMPALVDVVL
MTTLMLFQGE YTDPATGIRP ASHFDDVQSG MLSLYVLLTT ENYPDVMYPA FRLNQGFVVF
FVVFIFFGVY MLLSVAVAVI FDSFKVQRKK QALEDRIMER QALLAAFQCL PRTSDNSVTF
ETWHDLIETL KVQREEHEIK LLFSVIDQDG NGTVDVLEFF ELVDCLLLRF EVEASGPSSW
EAGLLTSWMY VPRPSLQKIV THKAFLNAVT VLIAFNIFVS CSIPNYPPRS PERAVFVYLD
YAILFLSCAE LLLRMAAWGF APFLRGVGTG STLSSSSSRS LRTFTDTFLK IGTPLYIVGG
LLLIVFYFYA ILGMEIWGAS LEEVPGYVDE VNAWATFSTP AHTFLLLFQL LTQSNWHDIM
FPALEAVGTK FASVYFVSFT FIVSNIVINV LVSLVLEIFL LARENSLLVH AELPLETDDG
DGNAHTSLLP PSSLDGAQDG GGEVSPGHDI ELDTAAFGVY DPACNSSEDD NGVTAHVRAS
PLESSSPHGA ESVRTNSASS LAYRGIAASA SGDLGSRINA VTVKGSDGGG PRAVRILQRQ
RYSRFIASQD MAGDASLDMS MLNTTALPGY DSLTPPATAS GATSHRSSRR HRSSSSKQGH
RLRSVANAVR LAHSSSSSTT SSTGAAGAAT PSSSSFSASS SSSPIGASLP NCENPNRVSP
VNDAPSPVAG AQPKEKPRPL LLSHHHRLHQ TRR
//
