ID A0A0L0DF20_THETB Unreviewed; 1956 AA.
AC A0A0L0DF20;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Acetyl-CoA carboxylase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AMSG_12051 {ECO:0000313|EMBL:KNC50937.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC50937.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC50937.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC50937.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL349463; KNC50937.1; -; Genomic_DNA.
DR RefSeq; XP_013756679.1; XM_013901225.1.
DR STRING; 461836.A0A0L0DF20; -.
DR EnsemblProtists; KNC50937; KNC50937; AMSG_12051.
DR GeneID; 25569966; -.
DR eggNOG; KOG0540; Eukaryota.
DR OrthoDB; 864at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:InterPro.
DR CDD; cd00185; TNFRSF; 1.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR InterPro; IPR034733; AcCoA_carboxyl_beta.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR011763; COA_CT_C.
DR InterPro; IPR011762; COA_CT_N.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR PANTHER; PTHR43842:SF2; BIOTIN-DEPENDENT ACETYL-_PROPIONYL-COENZYME A CARBOXYLASE BETA5 SUBUNIT; 1.
DR PANTHER; PTHR43842; PROPIONYL-COA CARBOXYLASE BETA CHAIN; 1.
DR Pfam; PF01039; Carboxyl_trans; 1.
DR Pfam; PF13517; FG-GAP_3; 2.
DR SUPFAM; SSF52096; ClpP/crotonase; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 2.
DR SUPFAM; SSF51126; Pectin lyase-like; 1.
DR PROSITE; PS50989; COA_CT_CTER; 1.
DR PROSITE; PS50980; COA_CT_NTER; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1956
FT /note="Acetyl-CoA carboxylase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005537452"
FT TRANSMEM 827..850
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1022..1045
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1057..1077
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1084..1103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1115..1138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1150..1174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1205..1226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1279..1299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1311..1329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1335..1355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1451..1707
FT /note="CoA carboxyltransferase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50980"
FT DOMAIN 1711..1953
FT /note="CoA carboxyltransferase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50989"
FT REGION 1702..1726
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1956 AA; 206052 MW; 8B851DAF57877459 CRC64;
MYAPVAILTL LVLVALSLAD DLPCTLVPDE TATDATSQLV GLATNMQHAY LAALDVDEDN
DIDLISSVPP LKLMRNQGDN TFVEENAAAA MSFTEPTGSG ITMGLAVADA NGDSLDDFVI
GWRDRNVLIM YFNIGGGSSA FTPHQLASAS QVGFPEFIDW DGDGDLDLVS FLWSTTGPAR
VFINSAGSWP TSPTYSFGSF TAVHPGSYGD FDGDNDLDMV VGNQKWRRDG PLSMTNIGTL
PGGLIGTSFS YQITTPINWN SDGHDDAGGG KGCYILLGDG AFGFTSQTLP IPDCIPTQER
IVVDVNKDGA HDMVYSASNR PDIGISLLVN DGSGNFASTI IRKSDRAVHT PFFVDVDGDG
DYDVFTSPWD NSDVDFGKLF FHENSARPGA HMPVFRSLCV VPGCTTVDGC VSNVIRIAQI
HGASDVELAA GVNYTQCPVT PITITNSALR IRPRGWSSRT SIRCGHAGVL FRVEHGAKAA
VERLDIFDTS TSFTVDPQPA ILVTGTASKL TLSNVTVTSA DATRDAAGLT LIASIVDGGF
LVAENSGSLV VESSDFVGCS ASGSGGAMAL KKTGLVSVTK TSFVGNSAVG GAGGAVVVVL
SDAVMGDTPL VSISNSVFAR NEARYGGVAA VILGPTILPT LEDHTFLPWQ PNQAAALAKA
SNLTVSFADV MLADNVASFG DVLYDCSAPV LGPGTPGGTV PGASSVFVCN PSDAATQAYS
SVPWVTSVGP EAGALVAAAA SPAVTIKRVD APANEPVLVM PGEELGGVSF GADDVFGSPT
TAGLVGLLPA PGSGDDVFMY VSNVLRALSA SETVVDFSRE RLAASHAGVV GSTVYMSAGL
AVAGAEVVFI PRPSLVVQFP LQFVACGPGW GASSTTPFAC SPCASGLFAP DTSMEACRPL
DDCLPNSKRT QSDSSECTCN AGYWAPALAP DTPCVVCPVG GICVGSSTEI PTAAVGYFNV
ANSTGSGALA EMAKCPRPQS CAGGSKCVTG SEGFMCRACS DGFYTDEDTV CRKCPNAAGA
MFYAFVSVLG AAVVLATAVV MWAAYGRGGG SSSVWRVPHA VKSGILFFQI LAVIGGAELN
WPSPLSYILA VFSAFNLSLA LFASECVLVD FATMYKFTAL IPMGMFLLVM AVAALFKFGL
RLRRVALPRV AERVLCILGP MLYIAAAHAS LVLFDCTKLP NGTFVLDADM GVVCFESEWI
ELLPYGLFAV VVYVIGLPAI LFTLLCRARH SLQTSEVRSR LGVLFLNFQP QFYLFEVLLL
LKRLAVVATA MFFSDLHVWL LTIFMVVFAV FAGIQLKYEP YKLQMYNDIE MQLNLVICAL
IMLGTLFWAD NFPNHTSLVL FAVIGCAAVF LALAFRLGMT AQVDVCNEPE AKEHGSPSLG
TSGTSSGSGL ALLTPQPVEL SYTMLRSVTT TATSLTSLPA VLRACTSALR GFSSSACVSA
GAFKPFLREG VSSGATAVEA ARAESLAGGG EKRVAAQHGK GKLTARERLD VLLDEGSFRE
MDPFVTHRCS DFGMEASKVP GDGVVTGQGT INGRLAFVFS QDFTVMGGSL SETHAEKICK
LMDNAMKVGV PVIGLNDSGG ARIQEGVASL AGYAEVFQRN VDASGVVPQI SMIMGPCAGG
AVYSPALTDF TFMVRDTSYM FVTGPEVVKT VTHEEVTQEE LGGAKTHATK SGVAHLTFED
DIEALLKLRE FYDFLPLSNT AEPPQRDFSD PRTRRSEQLN SIVPADPNSP YDIKSVITEL
VDDGEFFEIM PDFAKNIVIG FGRMEGKTVS FVANQPKELA GCLDIDASVK AARWIRFCDA
FNIPIATLVD VPGFLPGVGQ EHNGIIRNGA KLLHAYAEAS VPKVTVITRK AYGGAYTTLA
PRMLRADRVY GWPTSEVAVM GAKGAVGIIF RGDSDIAARE AEYEEKFLNP LPAARRGFLD
DVIEPAATRA IICEDLEVLA TKVEEGPAKK HSNGPL
//
