ID   A0A0L0DGZ8_THETB        Unreviewed;       568 AA.
AC   A0A0L0DGZ8;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=phosphatidylserine decarboxylase {ECO:0000256|ARBA:ARBA00012243};
DE            EC=4.1.1.65 {ECO:0000256|ARBA:ARBA00012243};
GN   ORFNames=AMSG_07526 {ECO:0000313|EMBL:KNC51614.1};
OS   Thecamonas trahens ATCC 50062.
OC   Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX   NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC51614.1, ECO:0000313|Proteomes:UP000054408};
RN   [1] {ECO:0000313|EMBL:KNC51614.1, ECO:0000313|Proteomes:UP000054408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC51614.1,
RC   ECO:0000313|Proteomes:UP000054408};
RG   The Broad Institute Genome Sequencing Platform;
RA   Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA   Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA   Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA   Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA   Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA   Ruiz-Trillo I., Lander E., Nusbaum C.;
RT   "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyruvate; Xref=ChEBI:CHEBI:15361;
CC         Evidence={ECO:0000256|ARBA:ARBA00001928};
CC   -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC   -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC       biosynthesis. {ECO:0000256|ARBA:ARBA00024326}.
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DR   EMBL; GL349468; KNC51614.1; -; Genomic_DNA.
DR   RefSeq; XP_013756010.1; XM_013900556.1.
DR   AlphaFoldDB; A0A0L0DGZ8; -.
DR   STRING; 461836.A0A0L0DGZ8; -.
DR   EnsemblProtists; KNC51614; KNC51614; AMSG_07526.
DR   GeneID; 25566424; -.
DR   eggNOG; KOG2420; Eukaryota.
DR   OrthoDB; 1216391at2759; -.
DR   UniPathway; UPA00558; -.
DR   Proteomes; UP000054408; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004609; F:phosphatidylserine decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR003817; PS_Dcarbxylase.
DR   InterPro; IPR033177; PSD-B.
DR   NCBIfam; TIGR00163; PS_decarb; 1.
DR   PANTHER; PTHR10067; PHOSPHATIDYLSERINE DECARBOXYLASE; 1.
DR   PANTHER; PTHR10067:SF6; PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL; 1.
DR   Pfam; PF02666; PS_Dcarbxylase; 2.
PE   4: Predicted;
KW   Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054408};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        74..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        111..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          362..407
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   568 AA;  62014 MW;  4454053D3708DF1B CRC64;
     MHATPPPTPP MTPRSIQHAL RARASAGASK VRASASSVVR TTLSVLQHSL SLSDRIVHWL
     IQSRLASRLL LPRNWLAITC LLILPYVAYL APSSQPGWAP LTLKVGLTSL ALWLAGQLLA
     TLTSIYVARR WVFIPRPTKG APLTSEPLVM VRRNATRKSW SPNRLKPPQV LRWDILGVGM
     SFMFGKITAI PLWRPLRAPI FSAWAKLFHA KVDEAEHALD HYASLQDFFT RALKPGLRPV
     ADSILTSPVD GTVVVVGPVE SDRVEQVKGV TYSLTQFLGQ DSATLIDSAS LPREADAHDD
     APGLPREVLD AQRVNDDDIA QEALELLSHS DGYDSASSLL SLTSHPVESL LTVIPESEIT
     LESQSELRMR SRGPSAQAGD NGPRAGSPAF AGPAGVDSGL GIAPEPDLSE PTTRLYHMVM
     YLAPGDYHRV HSPANVNFDT LRHFPGTLFP ISPIVARLIP DLFSLNERTL VGAYNVGSIQ
     INFDSQTKTN RLLRDFRCPN LELFSFGGVG CFAYNRNYEK PIELAKGEEL GLFNLGSTVV
     LVFEAPLDFE FTVGPGDKVR MGQAIGRV
//