ID A0A0L0DH18_THETB Unreviewed; 574 AA.
AC A0A0L0DH18;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=HORMA domain-containing protein {ECO:0000313|EMBL:KNC50598.1};
GN ORFNames=AMSG_00756 {ECO:0000313|EMBL:KNC50598.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC50598.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC50598.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC50598.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL349435; KNC50598.1; -; Genomic_DNA.
DR RefSeq; XP_013762485.1; XM_013907031.1.
DR AlphaFoldDB; A0A0L0DH18; -.
DR STRING; 461836.A0A0L0DH18; -.
DR EnsemblProtists; KNC50598; KNC50598; AMSG_00756.
DR GeneID; 25560546; -.
DR eggNOG; KOG4652; Eukaryota.
DR OrthoDB; 2915579at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR Gene3D; 3.30.900.10; HORMA domain; 1.
DR InterPro; IPR003511; HORMA_dom.
DR InterPro; IPR036570; HORMA_dom_sf.
DR PANTHER; PTHR48225; HORMA DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR48225:SF7; MEIOSIS-SPECIFIC PROTEIN HOP1; 1.
DR Pfam; PF02301; HORMA; 1.
DR SUPFAM; SSF56019; The spindle assembly checkpoint protein mad2; 1.
DR PROSITE; PS50815; HORMA; 1.
PE 4: Predicted;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408}.
FT DOMAIN 19..217
FT /note="HORMA"
FT /evidence="ECO:0000259|PROSITE:PS50815"
FT REGION 244..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 304..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 407..574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..266
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..283
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..429
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..499
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..568
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 574 AA; 61166 MW; FB2A0D5B9E5FC636 CRC64;
MVRSVAAAMA SATESVTASE SLCLVRNLLR CSISTIAYLR SLFPEHCFYD RTLNGLRIKS
LKPSTDEAQE LCNWLEQGVF PALKLGYIDH IILGVYEAAS DELVESYHFQ VQYPSGPDGL
PRYDAATPAP ATDQKEIKFS TITMMRTLTL LCQTLQPLVV DRYIMMRVIY SDTAPPDYEP
LFFQPAPANE PMFFTRKPLE FAVGSVRTHH HVYDMGMRTV LDGLADDEAS PPVAPAKLGV
FPADVPLGAS APSPSPSPLP QPPRPRPSPE SERDELSSLE ADTRRLEREN AALEAELARL
DDAARTAGPR IVGGSKRVTP PPPTPPGADT ASDNPRSDAQ LAAAVAFLAA ELRAGSDHVS
RRVLQDHLGL RTKDQGLAVM HNLRDLDLVA YSPSVGRWML QAAPIAAAAG KVNSPRRRLR
KRRRAKGNSR SLHPSSGSGL GTGSGSGSGS SPGSPKRRRT SLRSGLRSGS GLGSRLESRS
GSGSGSGSGS RSQSESPPRA SSPSPLPRGD PLRSVSQPVL GKNAAAAAAA ATRPRPRASV
VKHVLRVTSG TAPQPVSQLR SSASPASPLS PLHR
//
