ID A0A0L0DPS6_THETB Unreviewed; 2432 AA.
AC A0A0L0DPS6;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Myosin XI-2 {ECO:0000313|EMBL:KNC53433.1};
GN ORFNames=AMSG_08940 {ECO:0000313|EMBL:KNC53433.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC53433.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC53433.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC53433.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; GL349481; KNC53433.1; -; Genomic_DNA.
DR RefSeq; XP_013754468.1; XM_013899014.1.
DR STRING; 461836.A0A0L0DPS6; -.
DR EnsemblProtists; KNC53433; KNC53433; AMSG_08940.
DR GeneID; 25567515; -.
DR eggNOG; KOG0160; Eukaryota.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd00124; MYSc; 1.
DR CDD; cd00201; WW; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 1.25.40.530; MyTH4 domain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001202; WW_dom.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF00784; MyTH4; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 1.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00139; MyTH4; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51016; MYTH4; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000054408}.
FT DOMAIN 59..110
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 118..789
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 2280..2432
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 670..692
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT COILED 2128..2155
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 216..223
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 2432 AA; 266839 MW; 0CB29718FDD159AC CRC64;
MAAVSASSST GPGLDPEHDP SLWQELTTED GLVYYYNAGL DITQEDKPAC LRTDGDEAFD
GAWAWVPDEQ EGYVAGRVIE TNANDEPAVI ELIDGGTRRV PKKDQGSTFT LSPGSLRKNR
DDLVQMGEID EGIILHNLKK RFMEDTIYTN IGPILIIVNP YRWMKLYTEE IMEKVRNRGI
QMLKPHIFNI ADDAFRQLSE KMASGENPNQ SILISGESGA GKTEATKQAL KYLAHCAGSG
ETSGVEQKLL AANPLLEAFG NAATLRNHNS SRFGKWMEVF FDSRRRIVGA KINNYLLEKS
RVSHQIGGER NFHIFYQLCQ AREIAEMYSL GRAEEYAFVR GRTVIDDAHF SDAKDFAEVL
EAMDMFNIKE GADRQSIFRL VAGILHFGNL EFARDDSGEG SRIRNPETLA VAASMFCVPE
AALERAVLFR TLTFKRQDDV IVPLTPEQAA DNRNALARTL YNSMFNWLVV RVNQVLAPKG
GVGGLNLIGI LDIFGFEIFQ NNSFEQLCIN YANEKLQQHF NQHTFKMEQQ LYMDEGINFE
EVKFVDNQPC LDLLERKPHG ILIMLDEELL APSGSDDRFL DKLNSRHSKK TERFSMAFRT
PNTFNVEHYA GQVTYDVRGF LEKNKDTIEK DLLTLVHAST DQFIQHLFES VGADSKSRKQ
STAFQFRTQL GSLMKELQAT TPHYVRCIKP NSVFKPRIWS GRDSLLQLRY SGVFEAVRIR
QTGFPFRYSH AEFIRRYGVF NSWARKSSEA ATCKDILESV RGDFSEVQIG RTRVLYRAKM
HRALEVRLSI ILHRMATKAQ AAFRGFRARK LFAQMKKVDA AMRAAMATLD VDTLRAAISE
ARAMWFQLGV TDEAERLCAR LEEERGLNAA MERLRTAGDP EGNYEEIFRV ISRAEELGVV
NPDIAVLRES IRSIHERKQA VKDLEEGARE FDKKRLEAGL EAVSRLGISC AGAVATAQRV
LDLILSEESL VSRCSAALYS AQDDLQGLQE ALSEVSAFQI RTEAGKLLRS KLSATVGIRV
AIRDQDWDGL RSAVDAALAL GLAGMPDVVA AEEGLALRAR MAEVGSALVA EVPRKVLPAL
LAVLAQAREL EMGSSLYSSW RDEVAGAEAQ AAAHAALLED LRTQLKPLER TVTPARAVLE
LKTQIGVADE FGLVAQDDLA LVEAARTLLA VREGVSGKEW RKLENAVASA ARQPSIADHP
EVAAGKEGLA LRAKMLGVAG QLSTQMSARA MQGLAQALED AEALDMKTSY WSTWEDVVVA
GEVQLAQHKR IVKNLKACTG PGTQLQIDSL EAALADARAF GLRQPADTAL VSLGTLLLEL
RRALAARDWA VLGQCVARAA SSGISAPEVA QVKAGLELRE QMHEVASRLS VAKAKHDSEA
LRDAMGTAVR LEMEDSMWST WSELVVACEN QLRRHLELLR ALRATLAPGT SKLIDQLQSV
LNNVAAFGFK TRDDCVLEEQ GRITLSLRKA IAARAWDDIA GALASAAAAG YTSTEVSAAN
SGLELRAKME VVATKLSKAA AAHDAKAMAA DGYVILVDVV RTAGKVERQL VTHRAVVASL
KETTAPGTSK LVEPLQDAIE AATEYGLWTD LDADLLRGAE ITLQARIGFA SRDWEAVRKA
TQAAFVAGHE TSELRELAEG LKLRAKMSGV AEALRRAMEA HDAVALDAAL LDASGLRMES
SAWSTWQELM EKARAQRTQH ADLLSDLRHW LSAGKERAIE PLADALAAGV QYGFCVAEDV
QVLNEAKLVL QIRKGFDAKD YTSVRSQVRR ATQLGLASSR EIAAAAQVLE ARSQMEATAR
KLKAAAAAHD APALRAALVE ARGCEMGTSP HSSWVSEVVE AKELLSKHRS LLVRLRVAAA
PKSRNLIGPL AAALQEAIDF GLWTPADAGV QQNASIVLRA RQALDAQSWQ GLKAALDSAL
VAQLDNEEIR WYREGLALRH KMSAVAESLE RAVRSRDVDA LVAGVEEATT REVDMISSPW
SSWSPLVDSA AELAEEGKSL RTRLRSSLEP PAEVGDASAA EAAHLALLDA ADEYGFTLGD
DLELVRQSRL YHQVRVALRS SDWSRLEATL RSALSFGMES PELAAAAEAV HLARQRAEMA
ALLKSAMQDV YNYERNVLGM ALEQAEPLRL HESEYALLEQ EAKKLAAQIE TVRGSLESGT
ANVDAAELSV ALELAADIGY ETVQVASARV LLHEIQSIVD GASVALSTRD VKVLQQLLRR
AKMINLRAPP IPEIEMKLPL FVYSEGDKQV KDFERLRDAE SFASKKWFGR SSAAQSMLMW
SGSPLPNSLT QLDSAGEVKI ALQAFTNLLA YMGDRKSGGV FSSKKAGGEK PMRFLVELGR
GNSGSPLADE LYVQLVKQLS ENPHVESEAF GWRLMEAYVQ TFLPSAAFFV YLEWFLINQP
VVDGRPGAAQ YVAWLRGTRA EGAAGAASAS SA
//
