ID A0A0L0G1X3_9EUKA Unreviewed; 1493 AA.
AC A0A0L0G1X3;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=SH3 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SARC_05513 {ECO:0000313|EMBL:KNC82193.1};
OS Sphaeroforma arctica JP610.
OC Eukaryota; Ichthyosporea; Ichthyophonida; Sphaeroforma.
OX NCBI_TaxID=667725 {ECO:0000313|EMBL:KNC82193.1, ECO:0000313|Proteomes:UP000054560};
RN [1] {ECO:0000313|EMBL:KNC82193.1, ECO:0000313|Proteomes:UP000054560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP610 {ECO:0000313|EMBL:KNC82193.1,
RC ECO:0000313|Proteomes:UP000054560};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Young S.K., Zeng Q., Gargeya S., Alvarado L., Berlin A.,
RA Chapman S.B., Chen Z., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Howarth C., Mehta T., Neiman D.,
RA Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., White J., Yandava C., Burger G., Gray M.W., Holland P.W.H.,
RA King N., Lang F.B.F., Roger A.J., Ruiz-Trillo I., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Sphaeroforma arctica JP610.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KQ241950; KNC82193.1; -; Genomic_DNA.
DR RefSeq; XP_014156095.1; XM_014300620.1.
DR STRING; 667725.A0A0L0G1X3; -.
DR EnsemblProtists; KNC82193; KNC82193; SARC_05513.
DR GeneID; 25906017; -.
DR OrthoDB; 25371at2759; -.
DR Proteomes; UP000054560; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd00174; SH3; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR46026; RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F; 1.
DR PANTHER; PTHR46026:SF1; RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054560};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 446..507
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 623..876
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 98..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..404
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..558
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 750..808
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 922..942
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 990..1021
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1154..1197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1250..1397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..153
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 327..366
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 388..404
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..543
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..558
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..785
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 786..801
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1000..1020
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1174..1197
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1250..1308
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1316..1348
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1349..1382
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1493 AA; 161456 MW; 70FCB27249563202 CRC64;
MSSVIEALNW LLDQDNPEDE YDYDYYEYDN ESILSYSLDS AHHSGLKHEQ QYMHNQPQYQ
VRPRNGSGSG VVVYENQGVN IGMIVGVGHG GGQIVQARAT HTDTQPVTRG IIHPGTDERP
YADPRVLQSQ RDASSRYYTS QSDSEGGSYA TNTGVPKTAF DMSRLRDSVI VTSERNSHVS
MVSGVSVRSD KSDNADTAAD KVSHEVLLYD GDTEEDAHTR STYPDIHAHI YGGDEGGVAG
GKTDDDVNVS DNLPDSAVNQ LMVDPVVGVP AESENATSAN TTTNIKRVRD VVINGSVSSC
APSPKPRIFA KPRTCIKQAS ACTIDVSSNT GESMDNRTNC TDNQDQNDPD AGERTLSSNT
KSKTPGTPIP AKRAVIGAVP KKEPLTQPPN HPQTDNDSPQ KTAQEPIKTE EITLQEPINS
PEWAHKQVDQ HKAKHAGHPQ ETDHEFKPFQ AIAVHPYAAM RTDELSLCDG DLIEVVSCAS
EHWWEGRVLQ HGGSGWFPSV FVKVIESAEL SSLSERGSSA DGLEHASSTS SHSYHSADSG
IHTQMGERQR DGMEGTNKMR TRSIHTRSGV FVGGYGVDMR SQLKADDHSN IGIDTGAIST
PKGTRADKSG TFAYVDDRAM LNFRLMVGLD LINSEYDFTT EIELFLTNVA QPLKDLHTLP
DRPKRAILAP LFHVVQLHNM LYTQVYSECE GKDPFYGKVF LSLMPDIKKV YMEFASAHPV
ALEALRTYAD HADLNTLLNG VATSIPQGLD TTSEGDKQMH NNTTEPCMEG RTGTNTGTEC
IPEENTDNVA QRRDNGASKR ASHVSKKSTV SNNIKAQVNG IALSRLTLFS PFERLQKLVR
LFEELLRYTP DAHAHRHANE LVLQELSTLE RNCDTTRKLG EMERKVLLSN VVGLETSAIE
AMGKLEYAGT AVCQLLATST DTANSSSGKV SETKGEKSGT ATDGKVSWQE CVVLVFKSEL
LVLARVYDGV PSGNYSANAP VIVDMGSGVD PANRGGSRGN RRISADTSSF SSSSAVEAEP
VSKSDSHARP FVSGLSVFSY ELVERFDLVN SQVRYVTDAE VWATPNTTTT CTDTQKEMQG
GANVYEDKNT RNRQAVKCMS INQPIPDALC IESLEEAAHQ KIMLSSNSSR ENRESVQAVQ
LAIDLARARR GLEALSPQHV PSPVLERRAS GTPSHRLSGG SSRSGSGSHS LSGDSASGVL
ESEYSNVLNS VLSESVGRAN TESVGNTGTP PKLMKALSYD SSYGTNLNGT FDKRDAKSNG
ALSQNTNVHT NNSKPGLSAT SRDTNNTHAD GWKSNKGPAN SVGGSVSKSA SMGKKDKSKN
TSMQGLGRSK SKNRFSLGSW GSKHSKNSLN AQDTEKERER GASLKPAEEV AESIEEHDGE
DIPGISSQFT QDSRTSSSLS THLSVSVPIP GATASENLAH VGAIDALARG KGNKVTQEQF
GILCDTVVGL RAVMENMQKE MDGLRAHIVE EIKTRSVLEA RLKRCGAFGD GGV
//
